Cyclogyl (Cyclopentolate)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
1% Eye Drops
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Cyclogyl (Cyclopentolate) is a medication used to dilate the eye or cause ciliary paralysis. It works by preventing acetylcholine from causing muscle contractions in your eye muscle.

Store your Cyclogyl at room temperature and keep it out of reach of children.


Click here to watch an instructional video about using eye drops.

Avoid contaminating the tip of your dropper bottle. Do not touch it with bare hands. Avoid touching it to surfaces.

Always replace the cap immediately after use.

The usual dosing instructions for Cyclogyl are:

  • Instill 1-2 drops into the eye. May repeat in five to ten minutes if needed.


The active ingredient in Cyclogyl is cyclopentolate hydrochloride.

For a complete list of inactive ingredients, click here or check the product packaging.

Fact Table
Formula C17H25NO3
License US: FDA
Routes of administration Ophthalmic
Legal status Rx Only
Chemical Name Cyclopentolate
Elimination half-life 111 minutes
Dosage (Strength) 0.5%, 1%, 2%
Pregnancy Risk not ruled out
Brands Cyclogyl
Protein binding -
PubChem CID 2905
MedlinePlus a616014
ChEBI 4024
ATC code S01FA04
DrugBank DB00979
KEGG D07759
Bioavailability -


  • Carbachol
  • Pilocarpine
  • Ophthalmic cholinesterase inhibitors


Do not use Cyclogyl if:

  • You have a known allergy to any of the ingredients.
  • You have untreated narrow-angle glaucoma.

Cyclogyl can have adverse effects on the central nervous system. The effects can be particularly bad for younger patients.

If you are pregnant, breastfeeding, or considering becoming pregnant, talk to your doctor about the risks of using Cyclogyl.

Side Effects

  • Increased intraocular pressure
  • Burning
  • Photophobia
  • Blurred vision
  • Irritation
  • Hyperemia
  • Conjunctivitis
  • Blepharoconjunctivitis
  • Punctate keratitis
  • Synechiae
  • Psychotic disturbances
  • Ataxia
  • Incoherent speech
  • Restlessness
  • Hallucinations
  • Hyperactivity
  • Seizures
  • Disorientation
  • Skin rash
  • Drowsiness
  • Tachycardia
  • Hyperpyrexia
  • Vasodilation
  • Urinary retention
  • Diminished gastrointestinal motility
  • Decreased salivation


  1. DailyMed - Cyclogyl- cyclopentolate Hydrochloride solution/ DROPS. (2019). Retrieved May 25, 2020.
  2. Methods for Instilling Eye Drops. (2016). Retrieved May 24, 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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