Xeljanz XR (Tofacitinib)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Xeljanz is a prescription inflammation medication used for treating 3 different conditions caused by inflammation - rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It works by disrupting JAK (Janus Kinus) pathways in cells as a means of reducing the body’s inflammatory response. It is frequently prescribed for those who do not have a sufficient response with methotrexate or other arthritis medications. You can buy Xeljanz XR with a prescription at most pharmacies, and you may get a better Xeljanz XR cost ordering medication online from Canada.


For psoriatic arthritis treatment and rheumatoid arthritis treatment – either 5mg orally twice a day (immediate release) or 11mg orally once a day (extended release)

For ulcerative colitis treatment – therapeutic dose of 10 mg orally 2 times a day for initial 8 weeks; Maintenance dose: 5 mg orally 2 times a day.


The active ingredient in Xeljanz XR is Tofacitinib.


Xeljanz XR may not be safe for people with any history of liver disease (especially hepatitis B or C), kidney disease or renal failure, heart problems for those over 50, lung disease, blood clots, chronic infections, HIV, intestinal problems (like ulcers or diverticulitis), or diabetes.

You should delay or temporarily discontinue use of Xeljanz XR if you are planning to take a vaccine. Discuss this with your doctor before discontinuing use.

Inform your doctor if you have had tuberculosis before beginning on Xeljanz XR.

Do not take Xeljanz XR is you are pregnant or planning to become pregnant unless a doctor advises you to take it.


There is the possibility of drug interaction when taking Xeljanz XR along with; amlodipine atorvastatin, Cymbalta (duloxetine), folic acid, gabapentin, hydroxychloroquine, levothyroxine, lisinopril, losartan, Lyrica (pregabalin), meloxicam, methotrexate, omeprazole, pantoprazole, Plaquenil (hydroxychloroquine), prednisone, tramadol, trazodone, Vitamin B12 (cyanocobalamin), and Vitamin D3 (cholecalciferol)

Let your doctor know of all medications and supplements you are taking when discussing inflammatory arthritis medications with them and before proceeding to buy Xeljanz XR.

Side Effects

Xeljanz XR side effects are uncommon, but some people may experience diarrhea, headache, upper respiratory infections (like the common cold), or a rash. This medication may also raise your cholesterol levels.

In the event of severe Xeljanz XR side effects or ones that continue, stop using the medication and consult with your doctor again to discuss other inflammatory arthritis treatment options.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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