Wynzora ( Calcipotriene and Betamethasone dipropionate)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
0.005%/0.064% Cream
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Wynzora is a topical cream that contains calcipotriene, a vitamin D analog, and betamethasone dipropionate, a corticosteroid, to treat plaque psoriasis in patients who are 18 years old and older.


Wynzora comes in a tube that contains 0.005% calcipotriene and 0.064% betamethasone dipropionate. 50 mcg of calcipotriene and 0.644 mg of betamethasone dipropionate are contained in each gram of Wynzora cream.

Follow your prescription's instructions. Talk to your doctor or pharmacist about any questions or concerns you may have about your Wynzora prescription.

Apply Wynzora cream to the affected areas of the skin one time a day for up to 8 weeks. You should not apply more than 100 grams of cream per week. Avoid getting the cream on your face, groin, or armpit. Avoid getting the cream in your mouth, eyes, or vagina. You should not apply the cream to thin skin. Avoid using occlusive dressings unless your doctor instructs you to use them. 


Calcipotriene and betamethasone dipropionate are the active ingredients contained in Wynzora cream.


  • Before you start using Wynzora cream, it's important to tell your doctor:
    • About all the medications you take, including prescription, over-the-counter, vitamins, and herbal supplements
    • About your allergies
    • About your health problems
    • If you are pregnant or plan to become pregnant
    • If you are breastfeeding or plan to breastfeed
  • Elevated calcium levels in the blood or urine may occur with the use of Wynzora.
  • The endocrine system can be affected by Winzora, causing reversible suppression of the hypothalamic pituitary-adrenal (HPA) axis and a reduced production of glucocorticoids during and after treatment. You may be at a greater risk if you use a potent topical corticosteroid, use over a large area of skin or to occlusive areas, use for a long period of time, have skin barrier changes, have liver impairment, or you are young.
  • The risk of vision problems such as cataracts and glaucoma may be increased with the use of Wynzora. Tell your doctor right away if you experience any changes in vision.

Side Effects

Wynzora cream can cause side effects that include, but are not limited to, headaches, upper respiratory tract infection, and irritation at the site of application. Immediately call your doctor if you have side effects that worry you or persist.


Wynzora (calcipotriene and betamethasone dipropionate) cream, for topical use. Charleston, SC: EPI Health, LLC.; 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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