Kisqali (Ribociclib)

Prescription medicineOnly Available By Prescription

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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

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  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Kisqali (ribociclib) is a medication used to treat breast cancer. It works by disrupting the replication process of cancerous cells and decreasing the size of the tumor. Kisqali is often used in combination with other drugs as part of a cancer treatment program. You can buy Kisqali as a 200mg, 400mg, or 600mg tablet. Store your Kisqali tablets at room temperature and keep them out of reach of children.


  • Take Kisqali without regard to meals.
  • Do not chew or crush your Kisqali tablets. Swallow them whole.
  • You should take Kisqali at the same time every day.
  • Use Kisqali exactly as prescribed by your physician.
  • If you miss a dose, skip it and take your next dose as scheduled. Do not take multiple doses at the same time.
  • If you vomit after you take Kisqali, do not take another dose. Continue with your next dose as scheduled.
  • Your Kisqali dosage will depend on the type of breast cancer, other medications being used, and whether you are pre or post-menopausal. The usual dosage of Kisqali is 600mg once daily for 21 days, followed by 7 days without treatment.


The active ingredient in Kisqali is ribociclib. For a full list of inactive ingredients, see the package insert.

Fact Table
Formula C23H30N8O
License US: FDA
Routes of administration By mouth
Legal status Rx Only
Chemical Name Ribociclib
Elimination half-life 32 hours
Dosage (Strength) 200mg, 400mg, 600mg
Pregnancy Not assigned
Brands Kisqali
Protein binding 70%
PubChem CID 44631912
MedlinePlus a617008
ATC code L01XE42
DrugBank DB11730
KEGG D10883
Bioavailability -


  • Your doctor should check your blood cell counts, liver function, and heart function prior to starting treatment with Kisqali.
  • Do not take a Kisqali tablet that is broken, cracked, or otherwise not intact.
  • Do not take Kisqali if you have a known allergy to ribociclib or any other ingredient listed in the package insert.
  • Tell your doctor or seek emergency assistance immediately if you experience fainting or seizures while taking Kisqali. These symptoms can indicate a serious underlying heart condition.
  • Tell your doctor immediately if you experience any difficulty breathing or chest pain while taking Kisqali.
  • Kisqali should not be used during pregnancy. If you are pregnant or intend to become pregnant, discuss the risks with your doctor.
  • Avoid eating grapefruit or drinking grapefruit juice while taking Kisqali.
  • Kisqali can interact with other medications. Discuss all your medications with your doctor.

Side Effects

Common Kisqali side effects can include:

  • Hair loss
  • Itching
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Leukopenia
  • Neutropenia
  • Infectious disease
  • Joint pain
  • Back pain
  • Headache
  • Cough
  • Fatigue

Serious side effects of Kisqali can include:

  • Prolonged QT interval
  • Sudden cardiac death
  • Fainting
  • Anemia
  • Febrile neutropenia
  • High grade leukopenia
  • Lymphocytopenia
  • High grade neutropenia
  • Interstitial lung disease
  • Pneumonitis

Other Considerations

Compare the Kisqali cost at Canada Drugs Direct to your local drug store.


  1. Kisqali. (n.d.). Retrieved March 23, 2020
  2. DailyMed - kisqali- RIBOCICLIB TABLET, film coated. (2020). Retrieved March 23, 2020

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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