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Harvoni (Ledipasvir/Sofosbuvir)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Harvoni (ledipasvir/sofosbuvir) is a combination of drugs used to treat Hepatitis C infection. The two medications in Harvoni disrupt the replication processes of the Hepatitis C virus in complementary ways. Harvoni comes as a brand name product as well as a Harvoni generic product. You can buy Harvoni online as a 45mg/200mg or 90/400mg tablet. Store your Harvoni and Harvoni generic at room temperature and keep it out of reach of children.


  • You can take Harvoni with or without food.
  • Do not use antacid products within four hours of your Harvoni dose.
  • Do not crush or chew your Harvoni tablets.
  • The usual dosing instructions for Harvoni are:
    • Take one 90mg/400mg tablet by mouth once daily for twelve weeks.
      • Your dose could be lower if you have a liver condition.
      • Your doctor could use Ribavirin in combination with Harvoni.


  • The active ingredients are ledipasvir and sofosbuvir
  • For a full list of inactive ingredients, see the package insert.
  • Do not use Harvoni if you have a known allergy to any of the ingredients.
Fact Table
Formula C71H83F3N11O15P
License US: FDA
Routes of administration By mouth
Legal status Rx Only
Chemical Name Ledipasvir/Sofosbuvir
Elimination half-life 47 hours, 0.4 hours
Dosage (Strength) 90mg/400mg, 45mg/200mg
Pregnancy Not classified yet
Brands Harvoni
Protein binding >99.8%, 61-65%
PubChem CID 72734365
MedlinePlus a614051
ChEBI 85089, 85083
ATC code J05AP51
DrugBank DB09027, DB08934
KEGG D10578
Bioavailability -


Harvoni interacts with several medications. Let your doctor know if you currently use any of the following:

Side Effects


  1. DailyMed - HARVONI- ledipasvir and SOFOSBUVIR TABLET, film COATED HARVONI- ledipasvir and SOFOSBUVIR TABLET, film COATED HARVONI- ledipasvir and SOFOSBUVIR PELLET. (2020). Retrieved April 02, 2020
  2. Harvoni. (n.d.). Retrieved April 02, 2020

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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