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Diabeta (Glyburide)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Diabeta (Glyburide) is a medication used to treat type II diabetes. It works by causing your pancreas to increase the amount of insulin circulating in your blood.

Store your Diabeta at room temperature and keep it out of reach of children.


Take your Diabeta with your first meal of the day.

Take your Diabeta exactly as prescribed by your doctor.

The usual Diabeta dosage is:

  • Take 5mg by mouth once daily.
    • Depending on your results, your doctor could adjust your dose.


The active ingredient in Diabeta is glyburide. For a complete list of inactive ingredients, click here or check the product packaging.

Fact Table
Formula C23H28ClN3O5S
License US: FDA
Routes of administration By mouth
Legal status Rx Only
Chemical Name Glyburide
Elimination half-life 10 hours
Dosage (Strength) 1.25mg, 2.5mg, 5mg
Pregnancy No risk in other studies
Brands Diabeta
Protein binding 99.9%
PubChem CID 3488
MedlinePlus a684058
ChEBI 5441
ATC code A10BB01
DrugBank DB01016
KEGG D00336
Bioavailability -


  • NSAID drugs
  • ACE inhibitors
  • Disopyramide
  • Fluoxetine
  • Clarithromycin
  • Salicylates
  • Sulfonamides
  • Chloramphenicol
  • Probenecid
  • MAOI drugs
  • Beta adrenergic blockers
  • Bosentan
  • Miconazole
  • Fluoroquinolone antibiotics
  • Coumarin derivatives
  • Rifampin
  • Thiazide diuretics
  • Corticosteroids
  • Phenothiazines
  • Oral estrogens
  • Phenytoin
  • Nicotinic acid
  • Sympathomimetics
  • Calcium channel blockers
  • Isoniazid
  • Cyclosporine
  • Colesevelam


Do not use Diabeta if:

  • You have a known allergy to any of the ingredients.
  • You have any of the following conditions:
    • Type I diabetes
    • Diabetic ketoacidosis
  • You are currently taking bosentan.

If you are pregnant, breastfeeding, or considering becoming pregnant, talk to your doctor about the risks of using Diabeta.

Oral hypoglycemic drugs have been linked to an increased risk of cardiovascular fatality. Discuss your risk with your doctor.

You could be allergic to Diabeta if you have a sulfonamide allergy. Talk to your doctor about your risk.

Diabeta can cause a severe drop in your blood sugar. Ask your doctor about the signs and symptoms of hypoglycemia.

Patients with G6PD could develop hemolytic anemia while using Diabeta.

Side Effects

  • Hypoglycemia
  • Cholestatic jaundice
  • Hepatitis
  • Liver enzyme abnormalities
  • Nausea
  • Epigastric fullness
  • Heartburn
  • Allergic skin reactions
  • Pruritis
  • Erythema
  • Urticaria
  • Maculopapular eruptions
  • Erythema multiforme
  • Exfoliative dermatitis
  • Porphyria cutanea tarda
  • Photosensitivity
  • Leukopenia
  • Agranulocytosis
  • Thrombocytopenia
  • Hemolytic anemia
  • Aplastic anemia
  • Pancytopenia
  • Disulfiram-like reactions
  • Blurred vision
  • Angioedema
  • Arthralgia
  • Myalgia
  • Vasculitis


  1. DailyMed - glyburide tablet. (2019). Retrieved May 24, 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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