Canada Drugs Direct

Visiting from Canada?

Want to save up to 80% on your medications? Signup below to be notified if we open a Canadian Online Pharmacy.

I agree to receive email updates from Canada Drugs Direct

Looking for Call us toll free 1-800-500-2897

Crinone Gel 8%

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
8% x 90g
Pack Size
8% 1.45g applicators
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Crinone (Progesterone) gel is a topical hormone replacement product used in assisted reproduction technology or secondary amenorrhea. It works by supplementing your progesterone levels when applied vaginally.

You can buy Crinone gel online at Canada Drugs Direct as an 8% 90gm tube.

Store your Crinone at room temperature and keep it out of reach of children.


Follow the instructions provided in your product labeling.

  • Most applicators are intended for single-only

Wash your hands with soap and water before each use.

The usual dosage for Crinone gel is:

  • For Assisted Reproductive Technology
    • Apply Crinone 8% vaginally once daily (90mg dose)
      • Your doctor could increase your dose if needed.
    • For Secondary Amenorrhea
      • Apply Crinone 4% vaginally every other day for a total of six doses.
        • Your doctor could increase your dose to 8% if needed.


The active ingredient in Crinone gel is progesterone.

For a complete list of inactive ingredients, click here or check the product packaging.

Fact Table
Formula C21H30O2
License US: FDA
Routes of administration Vaginal
Legal status Rx Only
Chemical Name Progesterone
Elimination half-life 5-20 minutes
Dosage (Strength) 4%, 8%
Pregnancy -
Brands Crinone
Protein binding 96-99%
PubChem CID 5994
MedlinePlus a604017
ChEBI 17026
ATC code G03DA04
DrugBank DB00396
Bioavailability -


There are no drug interactions assessed in the product labeling. Give your doctor a complete list of medications you currently use.


You should not use Crinone if:

  • You have a known allergy to any of the ingredients.
  • You have had unusual menstrual bleeding and have not seen a doctor.
  • You have active liver disease or a history of liver disease.
  • You have breast or genital cancer.
  • You have had a miscarriage and could still have fetal tissue in the uterus.
  • You have a blood clot or a history of blood clots.

If you are pregnant, breastfeeding, or considering becoming pregnant, talk to your doctor about the risks of using Crinone.

Crinone can cause potentially fatal blood clotting.

Crinone can cause fluid retention. Talk to your doctor about the signs and symptoms of fluid retention.

Crinone therapy can cause glucose intolerance. Ask your doctor about your risk.

Side Effects

  • Blood clots
  • Pulmonary embolism
  • Stroke
  • Abdominal pain
  • Perineal pain
  • Cramps
  • Bloating
  • Headache
  • Fatigue
  • Increased appetite
  • Constipation
  • Diarrhea
  • Nausea
  • Joint pain
  • Depression
  • Mood swings
  • Sleep disorder
  • Nervousness
  • Decreased libido
  • Breast enlargement
  • Excessive urination at night
  • Vaginal discharge
  • Upper respiratory tract infection


Other Considerations

Compare our Crinone gel cost to your local drug store.

To share this product page with a friend or relative, have them search “Crinone gel 8 buy online”


  1. DailyMed - CRINONE- PROGESTERONE GEL. (2017). Retrieved May 23, 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews