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Caduet (Amlodipine / Atorvastatin)

Prescription medicineOnly Available By Prescription
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10/10mg
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10/20mg
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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

CADUET is a combination product that combines the medications NORVASC (amlodipine) and LIPITOR (atorvastatin). It is indicated for the treatment of both high blood pressure and high cholesterol. An advantage of buying CADUET is that it combines two medications that would normally be formulated in separate tablets.

Directions

The dose of CADUET is different for each person and should be taken based on how much of each ingredient the physician prescribed. CADUET is typically taken once per day and can be taken with or without food. The effects of CADUET and the individual ingredients will not be immediately noticeable, and the prescribing physician will measure blood pressure and test cholesterol to ensure the efficacy of the drug. The dose of CADUET will be adjusted by the physician based on the patient’s response.

Ingredients

Amlodipine

Amlodipine is indicated for the treatment of hypertension, or high blood pressure. The normal dose of amlodipine starts at 5 mg once daily and can be increased to a maximum of 10 mg once daily. Amlodipine is a calcium channel blocker. It works by slowing the influx of calcium ions into cardiac and vascular cells. Decreased transmembrane transfer of calcium ios lowers the contractile force of cardiac muscle and smooth vascular muscle, resulting in decreased blood pressure.

Atorvastatin

Atorvastatin is indicated for the treatment of high cholesterol levels and the usual dosage ranges from 10 mg daily to 80 mg daily. It works by competitively inhibiting HMG-CoA reductase, which is an enzyme that converts cholesterol precursors to active cholesterol molecules. Inhibition of this key enzyme during cholesterol synthesis causes a net decrease in circulating cholesterol.

The combination is used to lower both blood pressure and cholesterol in those with coronary artery disease and similar conditions. Lowering blood pressure and cholesterol has been shown to reduce the risk of cardiovascular events like stroke and heart attack.

Cautions

Atorvastatin, one of the primary active ingredients in CADUET, is CONTRAINDICATED in people with active liver disease.

Those with known hypersensitivity or allergic reaction to any of the active or inactive ingredients should not use CADUET.

Atorvastatin and similar medications may cause rhabdomyolysis (severe muscle breakdown) in rare cases. Those with a history of rhabdomyolysis should consider an alternative treatment. Atorvastatin has also been reported to cause immune-mediated necrotizing myopathy (IMNM) in rare cases. Anyone experiencing muscle aches and muscle weakness should speak with their physician. Other rare conditions that can arise from atorvastatin include endocrine dysfunction, CNS toxicity, and hemorrhagic stroke.

Amlodipine may worsen angina or acute myocardial infarction when starting or increasing the dose. Amlodipine may also cause hypotension, which is low blood pressure that causes symptoms like dizziness upon standing.

Side Effects

CADUET has the same possible side effects as the ingredients atorvastatin and amlodipine separately. Common side effects may include:

  • Diarrhea
  • Nausea
  • Swelling of the legs or ankles
  • Upset Stomach

The following side effects of CADUET are rare but serious. They should be reported to the physician or pharmacist and include:

  • Dark, amber-colored urine
  • Fatigue or tiredness
  • Liver problems
  • Loss of appetite
  • Low blood pressure
  • Muscle problems
  • Upper stomach pain
  • Yellowing of the skin and whites of the eyes

When buying CADUET, a prescription is required. Prior to buying CADUET, a physician or prescriber should be consulted to ensure this is the most appropriate treatment. This medication requires that a physician monitor treatment and treatment is usually lifelong. Buy CADUET from Canada Drugs Direct to receive the product at home for a great price and no wait in the pharmacy.

References

  1. DailyMed “AMLODIPINE package insert.” Nih.gov. Published 2017. Accessed October 22, 2019.
  2. DailyMed “ATORVASTATIN CALCIUM package insert.” Nih.gov. Published 2019. Accessed October 22, 2019.
  3. Pfizer. (2015). Caduet: Highlights of prescribing information. Print.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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