Most people will have used pain medication at some point in their lives. For minor pains, most individuals will opt for nonsteroidal anti-inflammatory drugs (NSAIDs), of which the best-known examples are Ibuprofen and Aspirin. However, in some situations, such as after surgery, these over-the-counter products may not be sufficient. While opioid pain medication and their associated risks of addiction are often considered the next step by default, you should be aware that another effective medication in treating moderate to severe pain is Toradol (ketorolac).

This article introduces you to Toradol injections, how they are used to provide short-term pain relief, how long one dose lasts, and how often you can get a Toradol injection.

About Toradol Injections

A Toradol injection is a nonsteroidal anti-inflammatory drug (NSAID), which serves as an alternative to opioids in managing moderate to severe pain. It’s non-addictive and often used to address the following:

• Post-surgery pain

• Injuries

• Kidney stones

• Trauma

• Inflammatory pain

Toradol’s active ingredient is ketorolac tromethamine. This chemical works by inhibiting the production of prostaglandins, which are responsible for triggering pain and inflammation. More specifically, it blocks cyclooxygenase (COX-1 and COX-2) enzymes, which create prostaglandins. Compared to many other NSAIDs, Toradol has a stronger impact on COX-1, which lowers prostaglandin levels. This leads to more effective pain relief as well as reduced swelling and fever.

How Long Does a Toradol Injection Last?

After intramuscular or intravenous administration, Toradol typically begins to relieve pain within 30-60 minutes and reaches its maximum effectiveness within one to two hours. Its effect usually starts to wear off after four to six hours.

Your dosing schedule and the frequency of Toradol injections depend on various factors, including your health, weight, and age. Healthy adults under the age of 65 can usually tolerate a daily maximum dose of 120 mg, administered intramuscularly (30 mg) or intravenously (15-30 mg), every six hours. The daily dose is usually cut in half, down to 60 mg and 15 mg IM or IV every 6 hours for high-risk patients. This includes those who are 65 years or older, under 100lb, or those with kidney impairment.

Due to its potential for severe side effects, Toradol injections are not approved for the treatment of chronic pain, such as arthritis and can be taken for a maximum of five days.

Safety Considerations

Toradol injections can have several mild to severe side effects. If you experience any concerning adverse reactions, please notify your healthcare provider immediately. These can include the following:

• Nausea

• Headache

• Dizziness

• Drowsiness

• Abdominal pain

• Diarrhea

• Swelling

• Bloating

• Stomach bleeding

• Kidney failure

Additionally, you should notify your healthcare provider of your medical history, such as existing medical conditions and other medications you are currently taking. Based on this information, they determine if this medication is safe and effective for you. For example, Toradol injections are typically unsuitable for those with a history of gastrointestinal ulcers, gastrointestinal bleeding, renal impairment, cardiovascular disease, or asthma.

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