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Zirgan Eye Gel (Ganciclovir)

Also Known as Virgan

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Zirgan is a prescription medication used to treat viral eye infections caused by the herpes simplex virus (HSV) in the eye. It is formulated as an ophthalmic gel to be applied topically in the eye.

Zirgan contains ganciclovir, an antiviral drug that inhibits the replication of HSV. It helps to reduce the severity and duration of the eye infection caused by the virus.

Fact Table




US DailyMed



Legal status


Chemical Name


Elimination half-life

2.5–5 hours

Dosage (Strength)



Consult Doctor


Zirgan Eye Gel

Protein binding

Less than 2%

PubChem CID






ATC code






Routes of administration

Eye Gel


Apply one drop into the eye five times daily for as long as directed by the doctor.


The active ingredient in Zirgan is ganciclovir.


Drug-drug interactions are not common with eye medications but can include:

  • Amphotericin B
  • Cladribine
  • CycloSPORINE (Systemic)
  • Didanosine
  • Fexinidazole
  • Ganciclovir-Valganciclovir
  • Imipenem
  • Leflunomide
  • Maribavir
  • Mycophenolate
  • Nitisinone
  • Pretomanid
  • Probenecid
  • Taurursodiol
  • Tenofovir Products
  • Teriflunomide
  • Zidovudine


Zirgan is intended for use only in the eyes and should not be ingested or applied to other body parts.

Contact lenses should not be worn while using Zirgan. If you wear contact lenses, remove them before applying the medication and wait at least 15 minutes before reinserting them.

Side Effects

Common adverse reactions include:

  • Abdominal distension
  • Abdominal pain
  • Alopecia
  • Anemia
  • Anorexia
  • Anxiety
  • Aphthous stomatitis
  • Arthralgia
  • Asthenia
  • Back pain
  • Bone marrow failure
  • Candidiasis
  • Cardiac arrhythmia
  • Catheter infection
  • Catheter sepsis
  • Cellulitis
  • Chest pain
  • Chills
  • Confusion
  • Constipation
  • Conjunctivitis
  • Cough
  • Decreased creatinine clearance
  • Depression
  • Dermatitis
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dysgeusia
  • Dyspepsia
  • Dysphagia
  • Edema
  • Elevated liver function tests
  • Eructation
  • Eye disease
  • Eye pain
  • Fatigue
  • Fever
  • Flatulence
  • Gastrointestinal perforation
  • Headache
  • Hematologic toxicity
  • Hematuria
  • Hypoesthesia
  • Hypotension
  • Hypertension
  • Increased serum creatinine
  • Infection
  • Inflammation at the injection site
  • Insomnia
  • Leukopenia
  • Malaise
  • Macular edema
  • Multiorgan failure
  • Muscle spasm
  • Myalgia
  • Myasthenia
  • Nausea
  • Neutropenia
  • Otitis
  • Pain
  • Paresthesia
  • Peripheral neuropathy
  • Phlebitis
  • Pruritus
  • Psychosis
  • Renal failure syndrome
  • Retinal detachment
  • Seizure
  • Sepsis
  • Skin rash
  • Thrombocytopenia
  • Tinnitus
  • Tremor
  • Upper respiratory tract infection
  • Urinary frequency
  • Urinary tract infection
  • Urticaria
  • Vasodilation
  • Vomiting
  • Weight loss
  • Xeroderma


Zirgan [package insert]. Irvine, CA: 9, Sirion Therapeutic; 2009.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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