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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zepzelca (lurbinectedin) is an alkylating drug indicated for the treatment of adults with metastatic small cell lung cancer (SCLC) who have progressed after platinum-based chemotherapy. It is a synthetic analog of trabectedin and functions by binding to the minor groove of DNA, disrupting transcription and leading to apoptosis in tumor cells. Zepzelca offers a treatment option for a population with limited therapeutic alternatives and has shown clinically meaningful responses in patients with relapsed SCLC, particularly those with platinum-sensitive disease.
| Fact Table | |
| Formula | C41H44N4O10S |
| License | US FDA (2020) |
| Bioavailability | Not applicable (IV only) |
| Legal status | Prescription only |
| Chemical Name | Lurbinectedin |
| Elimination half-life | 51 hours |
| Dosage (Strength) | 4 mg vial (administered at 3.2 mg/m² IV every 21 days) |
| Pregnancy | Not recommended – may cause fetal harm |
| Brands | Zepzelca |
| Protein binding | 99% |
| PubChem CID | 25154874 |
| MedlinePlus | a620047 |
| ChEBI | 61378 |
| ATC code | L01CX10 |
| DrugBank | DB12370 |
| KEGG | D11879 |
| Routes of administration | Intravenous (IV) |
Zepzelca is administered intravenously at a recommended dose of 3.2 mg/m² over 60 minutes every 21 days. It should be given by a qualified healthcare provider in a facility equipped to manage chemotherapy administration and related complications. Dosing may require adjustment based on hepatic function, hematologic parameters, and tolerability. Premedication with antiemetics is advised to manage nausea and vomiting. Routine monitoring of complete blood count (CBC), liver function tests, and renal function is necessary throughout treatment.
Each single-dose vial of Zepzelca contains:
Zepzelca must be reconstituted and diluted prior to intravenous infusion, following the manufacturer’s guidelines.
Zepzelca is contraindicated in patients with:
Myelosuppression, particularly neutropenia and thrombocytopenia, is a significant risk and may necessitate dose reductions or treatment delays. Hepatotoxicity, including elevations in ALT and AST, is common and requires close monitoring. Zepzelca may cause fetal harm; effective contraception is advised during treatment and for 6 months after the final dose for women and 4 months for men. The safety of Zepzelca in patients with moderate to severe renal impairment has not been fully established.
Common and potential side effects include:
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