Zegerid (Omeprazole and sodium bicarbonate)

Prescription medicineOnly Available By Prescription
Sezzle

Top Generic choice

Strength Pack Size Qty
Strength
20mg/1100mg
Pack Size
Qty
Strength
40mg/1100mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Omeprazole and sodium bicarbonate is a combination drug used:

  • For short-term treatment of active duodenal ulcers
  • For short-term treatment of active benign gastric ulcers
  • For the treatment of gastroesophageal reflux disease (GERD)
  • To maintain the healing of erosive esophagitis
  • To decrease the risk of upper gastrointestinal bleeding in patients who are critically ill

Fact Table

Formula

C17H19N3O3S

License

US DailyMed

Bioavailability

35–76%

Legal status

US: OTC / Rx-only

Chemical Name

Omeprazole

Elimination half-life

39.5 days

Dosage (Strength)

20mg/1100mg, 40mg/1100mg

Pregnancy

Consult Doctor

Brands

Zegerid

Protein binding

95%

PubChem CID

4594

MedlinePlus

a693050

ChEBI

7772

ATC code

A02BC01

DrugBank

DB00338

KEGG

D00455

Routes of administration

By mouth

Directions

Omeprazole and sodium bicarbonate come in a capsule and as a powder for oral suspension. It is available in 20 mg and 40 mg. Use as directed by the instructions on the prescription label.

The short-term treatment of an active duodenal ulcer dose: 20 mg taken by mouth once a day for 4 weeks

The short-term treatment of an active benign gastric ulcer dose: 40 mg taken by mouth once a day for 4 to 8 weeks

GERD (no erosive esophagitis) dose: 20 mg taken by mouth one time a day for up to 4 weeks 

GERD (erosive esophagitis) dose: 20 mg taken by mouth one time a day for 4 to 8 weeks

Dosing to maintain the healing of erosive esophagitis: 20 mg by mouth one time a day

Dosing to reduce the risk of upper gastrointestinal bleeding in patients who are critically ill (40 mg oral suspension only): 40 mg taken by mouth to start, then 40 mg taken by mouth 6 to 8 hours later and 40 mg by mouth one time a day afterwards for 2 weeks

Ingredients

The active ingredients in each capsule and oral suspension are omeprazole and sodium bicarbonate.

Contraindications

You should not take omeprazole and sodium bicarbonate if you have an allergy to any of its ingredients.

Cautions

  • Before you begin taking omeprazole and sodium bicarbonate, tell your doctor:
    • If you have any allergies
    • If you take any medications, including prescription and nonprescription medications, vitamins, and herbal supplements
    • If you have any health conditions
    • If you currently are pregnant or plan to become pregnant
    • If you are currently breastfeeding or plan to breastfeed
  • Achieving symptomatic relief with omeprazole and sodium bicarbonate does not rule out the presence of gastric cancer.
  • Atrophic gastritis may be caused by long-term treatment with omeprazole and sodium bicarbonate.
  • Kidney inflammation can be caused by omeprazole and sodium bicarbonate.
  • Vitamin B-12 deficiency can be caused by long-term treatment with omeprazole and sodium bicarbonate.
  • The risk of diarrhea associated with C. difficile can be increased by taking omeprazole and sodium bicarbonate.
  • Avoid taking omeprazole and sodium bicarbonate with clopidogrel, St. John's Wort, or rifampin.
  • The risk for hip, wrist, or spinal fractures can be increased by long-term treatment with omeprazole and sodium bicarbonate.
  • Low magnesium levels can be caused by long-term treatment with omeprazole and sodium bicarbonate.
  • Omeprazole and sodium bicarbonate can interfere with diagnostic investigations for Neuroendocrine Tumors.

Side Effects

Headache, stomach pain, nausea, diarrhea, vomiting, and flatulence are some of the most common side effects caused by omeprazole and sodium bicarbonate.

Immediately talk to your doctor if you have bothersome or persistent side effects.

Reference:

Omeprazole and sodium bicarbonate Prescribing Information. Raleigh, NC: Santarus, Inc.; 2014.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews