Zamine (Drospirenone - ethinyl estradiol)

Description

Zamine (Drospirenone - ethinyl estradiol) is a combination hormone medication prescribed as a contraceptive. It helps prevent pregnancy by changing the uterine lining and cervical mucus to make it difficult for sperm to reach the egg for fertilization. Zamine may help regulate the menstrual cycle and reduce premenstrual syndrome symptoms.

Directions

21-day regimen: Take one Zamine birth control pill every day at the same time for 21 consecutive days, then discontinue for 7 days. Expect withdrawal bleeding within 2-3 days after discontinuation. Resume on the 8th day, aligning with the same weekday the original course began.

28-day regimen: Take one active tablet daily for 21 days and then a hormone-free white tablet for 7 days. Withdrawal bleeding generally starts within 2-3 days after the final active yellow tablet. The next course starts promptly after the last, continuing on the same weekday the initial course initiated.

Ingredients

Each active pill of Zamine contains 3 mg of Drospirenone and 0.03 mg of ethinyl estradiol.

Contraindications

You may need to avoid Zamine if a medical history with any of the following apply:

• Severely high blood pressure
• Age over 35 years old
• Smoking
• Heart disease
• Stroke
• Heart attack
• Diabetes that affects the blood vessels
• Kidney or liver disease
• Cancer of the breast or endometrial lining
• Migraines with focal aura
• Abnormal cholesterol levels
• Known or possible pregnancy

Cautions

• Before starting Zamine birth control, tell your doctor about any of the following:
• Any known allergies you may have.
• All medications you take, including prescription, over-the-counter medications, and herbal supplements.
• Existing health problems, including but not limited to diabetes, chronic migraines, or mental disorders like depression.
• If you are pregnant or plan to become pregnant.
• If you are breastfeeding or have plans to breastfeed.
• Zamine might influence your blood sugar levels. Regular monitoring may be required if you have diabetes.
• Zamine may cause a rise in blood pressure. Regularly track your blood pressure and report any abnormal readings to your healthcare provider.
• There might be an increased risk of clotting issues with Zamine. Particular risks can include clots in the lungs, heart, intestines, or eyes.
• If you are prone to clotting issues due to injuries or extended illness, use caution. Consider non-hormonal contraceptive methods until you return to your usual activities.
• If you experience unexplained severe headaches or an increase in the frequency or intensity of migraines, notify your healthcare provider.
• Zamine has been linked to vision problems, both minor and severe. If you notice any eye-related concerns, including optic nerve swelling or vascular problems in the eye, seek medical attention right away.
• Should there be an increase in the occurrence of epileptic seizures, discontinue the medication and contact your healthcare provider.

Side Effects

Common Zamine side effects may include nausea, headaches, breast tenderness, and changes in weight or appetite. Some individuals may experience mood changes, such as increased depression or anxiety. More serious side effects may include blood clots, high blood pressure, or liver problems, although these are rare. Seek immediate medical attention if any unusual or severe side effects occur.

Consult a healthcare provider to understand all potential side effects, drug interactions, and warnings before starting birth control.

References:

Zamine Product Monograph. Toronto, ON: Apotex, Inc.; 2015.

About Dr. Gerardo Sison (Page Author)

An honors graduate of the University of Florida, Dr. Sison started his pharmacy career in a community setting, extending his services to hospitals and clinics over time. He has also worked in medication therapy management, advising patients on proper medication use for their chronic health conditions. Read More....