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Yaz Plus (Drospirenone/ Ethinyl Estradiol/ Levomef

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
28 days
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Yaz Plus (drospirenone/ethinyl estradiol/levomefolate) is a combination medication used for birth control, treating moderate acne in females at least 14 years old, and premenstrual dysphoric disorder (PMDD). It's also used to raise folate levels in women who choose to use an oral contraceptive for contraception.

Fact Table




Approved by the US FDA



Legal status


Chemical Name

Drospirenone, ethinyl estradiol, and levomefolate calcium

Elimination half-life

30-36 hours

Dosage (Strength)

28 days


Category X (not to be used during pregnancy)


Yaz Plus

Protein binding


PubChem CID






ATC code






Routes of administration



Yaz Plus is available in tablets containing 3 mg of drospirenone, 0.02 mg of ethinyl estradiol, and 0.451 mg of levomefolate calcium.

The recommended usage involves taking one pill every day at the same time, with some liquid as needed. The 28-pill pack contains 24 active and 4 inactive pills. When the pack is empty, start a new pack the very next day whether or not a menstrual period has occurred or is still in progress.


The active ingredients in Yaz Plus are drospirenone, ethinyl estradiol, and levomefolate calcium.


Discuss your medical history with your doctor. Do not take Yaz Plus if you have a history of blood clots, heart attack, stroke, or if you're at a high risk of these conditions. You should also avoid Yaz Plus if you have migraines, liver disease or tumor, cancer due to sex hormones, severe kidney problems, or unexplained vaginal bleeding. Do not take Yaz Plus if you are pregnant or allergic to drospirenone, ethinyl estradiol, levomefolate calcium, or any of the other ingredients in Yaz Plus.


  • Before you start taking Yaz Plus, inform your doctor: 
    • About any medications you take, particularly drugs for seizures, tuberculosis, HIV, or Hepatitis C, as they can affect Yaz Plus efficacy. 
    • About any medical conditions you have, including diabetes, hypertension, migraine, or depression. 
    • If you are going to have surgery or will be on bed rest. 
    • If you are pregnant or plan to become pregnant. Yaz Plus should not be used during pregnancy. 
    • If you are breastfeeding or plan to breastfeed. Small amounts of Yaz Plus may pass into breast milk. 
  • Yaz Plus may increase your risk of blood clots, stroke, or heart attack, especially if you smoke and are older than 35. 
  • Yaz Plus may cause brown, blotchy spots on your skin. Limit your exposure to the sun or ultraviolet light. 
  • Yaz Plus can increase your blood potassium levels. Contact your doctor if you experience irregular heartbeats or muscle weakness. 
  • Yaz Plus can cause depressive mood and mood swings. If you have a history of depression, closely monitor your condition while taking Yaz Plus.

Side Effects

The most common Yaz Plus side effects include nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet, and weight changes. If you experience any persistent or troublesome side effects, consult your doctor immediately.

Take Yaz Plus as prescribed, and make sure to discuss any questions or concerns you may have about Yaz Plus side effects or its usage with your healthcare provider.With a valid prescription, you can buy Yaz Plus pills online at affordable prices here!


  1. Yaz Plus Prescribing Information. Bayer HealthCare Pharmaceuticals Inc.; 2020.
  2. Yaz Plus (Drospirenone/ Ethinyl Estradiol/ Levomefolate) Important Safety Information. Accessed July 22, 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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