Xtandi (Enzalutamide)

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Xtandi is a prescription medication for prostate cancer treatment that slows the cancer's progress by preventing androgen from connecting with androgen receptors in the prostate cells. The outlook for treatment is improved due to the tumor growing more slowly and the individual may not require a prostatectomy. Enzalutamide is part of the anti-androgen class of drugs and it is most commonly prescribed for men who have insufficient results from hormone therapy or surgical treatments to lower testosterone.

You can by Xtandi with a prescription, and your lowest Xtandi cost will be when you order medication online from Canada Drugs Direct.

Fact Table




FDA approved


Approximately 84%

Legal status

Prescription medicine

Chemical Name


Elimination half-life

5.8 days

Dosage (Strength)

40 mg capsules

Pregnancy advice

Not recommended; use effective contraception



Protein binding


PubChem CID






ATC code






Routes of administration



Standard dosage is to take one Xtandi tablet 1x a day and taken at the same time every day. Medication can be taken with or without food. Tablets should be swallowed whole; they should not be crushed, chewed, or dissolved in a liquid.

Dosage may vary based on your condition, and patients should always take their medication exactly as indicated in the prescription.


The active ingredient in Xtandi is Enzalutamide.


Inform your doctor of any history of high blood pressure, seizures, brain injury, stroke, brain tumors, heart disease, heart attack, diabetes, high blood cholesterol or fats (triglycerides) or broken bones before beginning on Xtandi medication.

Medication should not be used by women who are pregnant or breastfeeding. Men with a pregnant wife or partner should use a condom during sexual activity while using enzalutamide treatment and for 3 months after treatment finishes. Men with a female partner of childbearing age who is not pregnant should use a condom and another form of birth control while using this medication and for 3 months after their end of treatment with the medication.


Negative drug interactions are possible between Xtandi and other Rx medications, including rifabutin / rifampin / phenobarbital / phenytoin / asunaprevir / cobicistat / dihydroergotamine, / ergotamine / fentanyl / lurasidone / pimozide / quinidine / sirolimus / suvorexant / tacrolimus / voriconazole.

The herbal OTC supplement St. John's Wort also has an interaction risk with this medication.

Inform your doctor of all medications and supplements you are currently taking before getting a prescription and proceeding to buy Xtandi online.

Side Effects

Side effects from Xtandi are not common, but some users may experience hot flashes, headache, dizziness, or decreased sexual interest or ability. If side effects are experienced it may be best to discontinue use and talk to your doctor about other prostate cancer treatment medication options.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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