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Xigduo (Dapagliflozin / Metformin)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Xigduo is a medication prescribed to treat adults with type 2 diabetes; it is used in combination with diet and exercise. Dapagliflozin and metformin are the two medications that are contained in Xigduo.

Xigduo comes in the following strengths of oral tablets:

  • 5 mg dapagliflozin/850 mg metformin
  • 5 mg dapagliflozin/1,000 mg metformin


Xiduo should be taken as your doctor has directed. Speak with your doctor or pharmacist if you have any questions or concerns.

It is recommended to take one tablet orally twice daily; it should not be taken on an empty stomach.


Dapagliflozin and metformin are the active ingredients in Xigduo.


Avoid taking Xigduo if you are experiencing any of the following:

  • Acute metabolic acidosis (increased acid levels in the blood)
  • Diabetic precoma
  • Liver impairment
  • Kidney impairment, dehydration, severe infection, or shock
  • Low oxygen levels, heart failure, lung failure, or you had a recent heart attack
  • Alcohol intoxication or you drink increased amounts of alcohol


  • Before beginning treatment with Xigduo, tell your doctor about:
    • Any and all prescription and over-the-counter medications you take
    • Any allergies you have
    • Your past medical history and current health conditions
    • If you are currently pregnant or breastfeeding

Side Effects

If Xigduo is taken with insulin or another antidiabetic medication, there is an increased chance of experiencing low blood sugar. Gastrointestinal problems are another possible Xigduo side effect. These are not the only side effects that can occur. If you experience concerning or persisting side effect, immediately talk to your doctor.


  1. Xigduo. European Medicines Agency; 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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