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Xenical (Orlistat)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Xenical is a prescription medication used to help induce weight loss in patients on a calorie-reduced diet. 

Xenical should only be used under the supervision of a trained healthcare professional. 

Xenical works by blocking the action of enzymes that help to digest food. Xenical prevents the absorption of food into the bloodstream from the gastrointestinal tract, reducing the overall caloric intake.


The usual dose of Xenical is 120 mg by mouth three times daily with meals. Xenical may be taken during the meal or up to one hour later.


The active ingredient in Xenical is orlistat.


Common drug-drug interactions with Xenical may include: 

  • Amiodarone
  • Atazanavir
  • Carbamazepine
  • Cyclosporine
  • Darunavir
  • Fosamprenavir
  • Gabapentin
  • Indinavir
  • Lamotrigine
  • Levetiracetam
  • Levothyroxine
  • Lopinavir
  • Multivitamins
  • Nelfinavir
  • Phenytoin
  • Propafenone
  • Ritonavir
  • Sincalide
  • Triheptanoin


Patients should take a multivitamin containing fat-soluble vitamins while taking Xenical; including Vitamins A, D, E, and K.

Tell your prescriber if you have a history of liver disease or gout before starting Xenical.

Ask your doctor or pharmacist for a full list of precautions when taking Xenical.

Side Effects

Some of the most common adverse reactions from Xenical may include:

  • Abdominal distress
  • Abdominal pain
  • Anxiety
  • Bowel urgency
  • Fatigue
  • Fecal incontinence
  • Flatulence with discharge
  • Frequent bowel movements
  • Gingival disease
  • Headache
  • Infectious diarrhea
  • Influenza
  • Low blood sugar
  • Menstrual disease
  • Nausea
  • Oily evacuation
  • Oily rectal leakage
  • Otitis
  • Pedal edema
  • Rectal pain
  • Sleep disorders
  • Steatorrhea
  • Urinary tract infection
  • Vaginitis
  • Xeroderma


  1. Xenical [package insert]. San Francisco, CA: Genentech; 2012.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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