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Wellbutrin XL (Bupropion)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


WELLBUTRIN XL (bupropion) is a medication prescribed to treat major depressive disorder (MDD); it can also be prescribed to prevent seasonal affective disorder (SAD). WELLBUTRIN XL works by increasing the concentration of dopamine and noradrenaline in the brain and central nervous system (CNS) cells. How the modulation of dopamine and noradrenaline treat MDD and SAD is not well understood by clinicians and researchers.

MDD is a complex disease with many causative factors and symptoms. People with MDD have a prolonged and abnormally depressed mood that adversely impacts social, occupational, and functional areas of their life.

Behavioral and mood symptoms of MDD may include:

  • Decreased energy
  • Feelings of emptiness
  • Feelings of hopelessness
  • Guilt
  • Helplessness
  • Irritability
  • Sadness
  • Worthlessness

Physical symptoms of MDD may include:

  • Appetite changes
  • Headaches
  • Suicidal thoughts and/or suicidal actions
  • Trouble sleeping
  • Unexplained physical symptoms without a clear cause
  • Weight changes

People with MDD may experience some or all of these symptoms. Different symptoms may be present during different "episodes" of the disease.

Fact Table







Legal status


Chemical Name


Elimination half-life

11–21 h

Dosage (Strength)

150mg, 300mg


Consult Doctor



Protein binding


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ATC code






Routes of administration

By mouth


Take WELLBUTRIN XL exactly as prescribed by your physician. The dose of WELLBUTRIN XL usually ranges from 150 mg to 300 mg once daily.


The active ingredient of WELLBUTRIN XL is bupropion hydrochloride.


Patients with a seizure disorder or history of seizures should use caution while taking WELLBUTRIN XL. The dose should be limited to a maximum of 450 mg daily.

Patients with cardiovascular disorders should use caution while taking WELLBUTRIN XL as it can increase blood pressure. Your doctor should monitor blood pressure before starting and during treatment.

WELLBUTRIN XL can cause or worsen narrow-angle glaucoma.

Side Effects

Common adverse effects of WELLBUTRIN XL may include:

  • Abdominal pain
  • Agitation
  • Anorexia
  • Anxiety
  • Dizziness
  • Dry mouth
  • Increased urinary frequency
  • Insomnia
  • Myalgia
  • Nausea
  • Palpitation
  • Pharyngitis
  • Rash
  • Sweating
  • Tinnitus
  • Tremor

WELLBUTRIN XL is only available by prescription from a licensed physician.


  1. Valeant Pharmaceuticals. Wellbutrin XL[package insert]. U.S. Food and Drug Administration website. Revised 2017. Accessed December 22, 2019.

Frequently Asked Questions about Wellbutrin XL

What is Wellbutrin XL used for?

Wellbutrin XL is used to treat major depressive disorder and seasonal affective disorder.

Is Wellbutrin XL a strong antidepressant?

Wellbutrin XL is a moderate-strength antidepressant. Its effectiveness varies, so consult a healthcare professional for the right treatment.

What are the cons of Wellbutrin XL?

Potential side effects include dry mouth, blurred vision, nausea, weight loss, sleep disturbances, seizures, mood changes, and irregular heartbeats.

How does Wellbutrin XL make you feel?

Wellbutrin XL affects people differently. It can improve mood and energy but may also cause anxiety or restlessness. Monitor and discuss any changes with your doctor.

What is the biggest side effect of Wellbutrin?

Seizures are a significant side effect of Wellbutrin XL, along with an increased risk of suicidal thoughts. Close monitoring is essential.

How fast is weight loss on Wellbutrin XL?

Weight loss varies. Some may experience gradual loss due to effects on appetite and metabolism. Consult your healthcare provider for guidance.

What happens if you miss a dose of Wellbutrin XL?

Taking Wellbutrin unnecessarily can cause side effects. Follow your doctor's recommendations and avoid self-medication.

What happens if you take Wellbutrin and don't need it?

Taking Wellbutrin when not needed can lead to unnecessary side effects. Always follow your doctor’s recommendations and avoid self-medicating.

Can I drink while on Wellbutrin?

Moderate alcohol consumption is generally safe, but excessive drinking can increase the risk of seizures and other side effects.

Does Wellbutrin help with brain fog?

Wellbutrin XL may improve cognitive function for some, potentially reducing brain fog.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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