Vectical Ointment (Calcitriol)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
3mcg/gm 100g
Pack Size
Qty
What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Vectical Ointment is a topical formulation of calcitriol (the active form of vitamin D3) indicated for the treatment of mild to moderate plaque psoriasis in adults and children aged 2 years and older. Calcitriol modulates keratinocyte proliferation and differentiation, as well as local immune responses, making it effective in reducing the scaling, redness, and thickness of psoriatic lesions. Unlike some other vitamin D analogs, Vectical has demonstrated low potential for causing hypercalcemia, allowing for safe topical use in chronic management.

Fact Table

Formula

C27H44O3

License

US FDA (2009)

Bioavailability

Minimal systemic absorption (topical use)

Legal status

Prescription only

Chemical Name

(1a,25-dihydroxycholecalciferol) Calcitriol

Elimination half-life

~5–8 hours (systemic exposure)

Dosage (Strength)

3 mcg/g ointment (0.0003%)

Pregnancy

Category C – use only if clearly needed

Brands

Vectical

Protein binding

>99.9%

PubChem CID

5280453

MedlinePlus

a682335

ChEBI

CHEBI:17823

ATC code

D05AX04

DrugBank

DB00136

KEGG

D00137

Routes of administration

Topical

Directions

Apply a thin layer of Vectical Ointment to affected skin areas twice daily, morning and evening.

  • Do not apply to the eyes, lips, or face, and avoid use in the underarm or groin areas unless directed by a physician.
  • Limit to a maximum of 200 grams per week in adults and 100 grams per week in children ages 2–6 years.
  • Wash hands thoroughly after application.
  • Continue use as prescribed, with periodic evaluation by a healthcare provider.

Ingredients

Each gram of Vectical Ointment contains:

  • Calcitriol 3 mcg (0.0003%)

Inactive ingredients:

  • Mineral oil, white petrolatum, DL-alpha-tocopherol (vitamin E), butylated hydroxytoluene (BHT)

Contraindications

Vectical is contraindicated in:

  • Patients with known hypersensitivity to calcitriol or any component of the formulation
  • Patients with hypercalcemia or evidence of vitamin D toxicity

Cautions

Use caution in patients with conditions that predispose to hypercalcemia (e.g., sarcoidosis, severe renal impairment). Serum calcium levels should be monitored in patients using large quantities or those receiving other forms of vitamin D. Avoid excessive exposure to natural or artificial sunlight, as calcitriol may increase photosensitivity. Safety in pregnancy has not been established—use only if clearly needed. Avoid concomitant use with other topical psoriasis therapies without medical supervision.

Side Effects

Most patients tolerate Vectical well. Possible side effects include:

  • Mild skin irritation (itching, redness, burning)
  • Dryness at the application site
  • Hypercalcemia or hypercalciuria (rare)
  • Worsening of psoriasis (rare)
  • Allergic reactions (very rare)

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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