Vaseretic (Enalapril/HCTZ)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Vaseretic is a combination medication; it contains enalapril and hydrochlorothiazide to help lower blood pressure.

Enalapril maleate, an angiotensin-converting enzyme (ACE) inhibitor, inhibits the production of angiotensin II; this results in blood vessel dilation and reduction in blood pressure. Hydrochlorothiazide, a thiazide diuretic–or fluid pill–acts on the kidneys to get rid of extra water and sodium, leading to increased urine output and lower blood pressure.

Vaseretic comes in an oral tablet containing 10 mg of enalapril maleate and 25 mg hydrochlorothiazide.

Fact Table




US DailyMed


No effect

Legal status


Chemical Name

Enalapril – Hydrochlorothiazide

Elimination half-life

5.6-14.8 hours

Dosage (Strength)



Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Vaseretic medication should be taken as your doctor has directed. Contact your doctor or pharmacy regarding any questions or concerns you have about the medication.

Your blood pressure goals and medication tolerance will determine how much Vaseretic you will be prescribed. The usual dosage range is enalapril 10 mg to 40 mg and hydrochlorothiazide 12.5 mg to 50 mg by mouth daily.


The active ingredients in Vaseretic are enalapril maleate and hydrochlorothiazide. Iron oxide, lactose, magnesium stearate, sodium bicarbonate, and starch are the inactive ingredients.


If you have an allergy to Vaseretic or to any of its ingredients, avoid the medication.

Avoid taking Vaseretic with a neprilysin inhibitor such as sacubitril. If you are switching to sacubitril/valsartan, wait at least 36 hours after taking your last dose of Vaseretic before you start taking sacubitril/valsartan. If you are switching to Vaseretic, wait at least 36 hours after taking your last dose of sacubitril/valsartan before you start taking Vaseretic.


Vaseretic has the following Boxed Warning:

  • Because Vaseretic can injure or cause death to a developing fetus, the medication should be discontinued once pregnancy is detected.
  • Before you begin taking Vaseretic, tell your doctor about:
    • All the medications you take
    • Your allergies
    • Your health problems
    • Your past medical history
    • Any planned surgeries and procedures
    • Your pregnancy or breastfeeding status
  • Low blood pressure can occur during Vaseretic treatment.
  • Vaseretic can cause anaphylactoid reactions. In addition, patients on ACE inhibitors who are undergoing desensitizing treatment or high-flux membrane exposure may develop these reactions.
  • ACE inhibitors can cause angioedema, or swelling. If you experience swelling of the face, arms, legs, lips, tongue, and/or throat, get emergency care right away. If you develop stomach pain, get medical attention right away, as intestinal angioedema can also occur.
  • Liver problems can develop during treatment with ACE inhibitors; however, this is a rare occurrence.
  • A buildup of nitrogen waste products in patients with kidney disease can be caused by thiazide diuretics.
  • Caution using thiazide diuretics should be used by patients with liver problems.
  • Sensitivity reactions can occur in patients with bronchial asthma.
  • Lupus may present or get worse.
  • Lithium and thiazide diuretics should not be taken together.
  • Vision problems, including glaucoma, may occur with thiazide diuretic use. If patients experience vision problems, they should get medical attention immediately.
  • Vaseretic should be used with caution in patients with certain heart problems.
  • Kidney problems can be caused by Vaseretic.
  • High potassium levels in the blood can be caused by Vaseretic.
  • A dry cough that is due to the enalapril component of Vaseretic can develop.
  • Abnormal electrolyte levels can be caused by Vaseretic.

Side Effects

Common Vaseretic side effects include dizziness, headache, fatigue, and cough. Other side effects may also occur. Contact your doctor if you have side effects that bother you or won’t go away.

With a valid prescription from your doctor, you can buy Vaseretic online at a competitive price at Canada Drugs Direct.


Vaseretic. Bridgewater, NJ: Valeant Pharmaceuticals North America LLC; 2017.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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