Valtrex (Valacyclovir)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe Valtrex to treat or prevent different viral infections. Valtrex belongs to a class of medications called antivirals

Valtrex is primarily given to treat infection with different types of herpes viruses. Specifically, it can be used to treat cold sores, genital herpes, and herpes zoster (shingles). It can also be taken every day to prevent viral infections in people with HIV whose immune systems are compromised.

Valtrex works by preventing herpes viruses from replicating and making new viruses. It attaches to viral DNA to prevent the infection from spreading further. This slows down the infection enough for the immune system to contain the infection.


The amount you should take will be determined by the doctor and depends on what you are treating.

For cold sores, the normal dose is 2 grams every 12 hours for one day.

For the first outbreak of genital herpes, take 1 gram twice daily for ten days. 

For subsequent outbreaks of genital herpes, take 500 mg twice daily for three days.

For viral suppression, the normal dose is 500 mg by mouth once daily.

Take each dose of Valtrex with a full glass of water.


The active ingredient in Valtrex generic is Valacyclovir.


Some of the more common interactions that happen with Valtrex include:

  • Cladribine
  • Clozapine
  • Foscarnet
  • Mycophenolate
  • Tenofovir
  • Theophylline
  • Tizanidine
  • Varicella vaccine
  • Zidovudine
  • Zoster vaccine

Fact Table







Legal status

US: RX Only

Chemical Name


Elimination half-life


Dosage (Strength)

500mg (42 tablets), 1000mg (42 tablets)


Consult a doctor



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth (tablets)


Older patients may experience an increased amount of side effects.

The dose may need to be decreased in people with poor kidney function.

Side Effects

Some of the most common Valtrex side effects can include:

  • Abdominal pain
  • Arthralgia
  • Decreased hemoglobin
  • Dehydration
  • Depression
  • Diarrhea
  • Dizziness
  • Dysmenorrhea
  • Fatigue
  • Fever
  • Headache
  • Increased liver enzymes
  • Increased serum creatinine
  • Leukopenia
  • Nasopharyngitis
  • Nausea
  • Neutropenia
  • Rhinorrhea
  • Skin rash
  • Thrombocytopenia
  • Vomiting


Valtrex [package insert]. Greenville, NC: GlaxoSmithKline; 2008.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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