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Uloric (Febuxastat)

Prescription medicineOnly Available By Prescription
Sezzle

Top brand choice

Strength Pack Size Qty
Strength
80mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
Strength
40mg
Pack Size
Qty
Strength
80mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Uloric is a medication your healthcare provider may use to treat gout flare-ups. Gout is a condition where uric acid, a byproduct of metabolism, builds up too much in the joints. The joints that are typically affected include the toes, ankles, and knees. 

In high concentrations, uric acid forms crystals that cause pain, swelling, and redness in the affected joints.

Uloric works by reducing the amount of uric acid that accumulates in the bloodstream and joints. By reducing the buildup of uric acid, Uloric works to reduce pain and swelling in people with gout symptoms.

Fact Table

Formula

C16H16N2O3S

License

US FDA

Bioavailability

49%

Legal status

US: RX Only

Chemical Name

Febuxastat

Elimination half-life

5 to 8 hours

Dosage (Strength)

40mg, 80mg

Pregnancy

No known risks

Brands

Uloric and Adenuric

Protein binding

99% %

PubChem CID

134018

MedlinePlus

a609020

ChEBI

31596

ATC code

M04AA03

DrugBank

DB04854

KEGG

D01206

Routes of administration

By mouth (tablets)

Directions

Take Uloric exactly as prescribed by your doctor.

The recommended starting dose is 40 mg by mouth once daily but can be increased to 80-120 mg by mouth.

While starting Uloric, gout flares may increase at first. Your doctor may prescribe additional medications to manage this. After the first few weeks or months of treatment, your doctor may stop the second medication if it is no longer needed.

Ingredients

The active ingredient in Uloric generic is Febuxostat.

Interactions

Before taking Uloric, tell your doctor and pharmacist about all medications you are taking. Common drug-drug interactions may include:

  • Azathioprine
  • Didanosine
  • Mercaptopurine
  • Methotrexate
  • Pegloticase
  • Theophylline

Cautions

Tell your doctor if you have a history of liver problems before taking this medication. Uloric has caused liver damage in some people, so your doctor should monitor liver labs before and during treatment.

Tell your healthcare provider if you have a history of cardiovascular disease. Uloric has been associated with increased rates of embolism (blotting disorder) in some patients.

Side Effects

The following are common Uloric side effects.

  • Acute gout attack
  • Arthralgia
  • Hepatic insufficiency
  • Increased liver enzymes
  • Nausea
  • Skin rash

References

  1. Uloric [package insert]. Deerfield, IL: Takeda; 2017.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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