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Tylenol Extra Strength Tablets


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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Tylenol Extra Strength is a widely recognized over-the-counter (OTC) medication used to alleviate a range of common aches and discomforts. The main pain-relieving ingredient is acetaminophen, Tylenol should only be used as a temporary remedy for pain management.

The active ingredient, acetaminophen, works by interfering with pain signals in the brain called prostaglandins. It also helps to lower fever and ease mild to moderate pain associated with headaches, muscle aches, backaches, and toothaches.


Take Tylenol extra strength exactly as directed by your prescriber or the directions on the box.

The usual directions are 1000 mg every 4-6 hours as needed for pain. Do not take more than 3000 mg in a day.

If you are taking this drug for long periods or in higher than prescribed doses, speak with your physician. By following proper usage guidelines and being mindful of possible interactions, you can safely benefit from its pain-relieving properties.


The active ingredient in Tylenol Extra strength is Acetaminophen 500 mg.


The most common interactions with Tylenol include

  • Alcohol (Ethyl)
  • Busulfan
  • CarBAMazepine
  • Dapsone (Topical)
  • Dasatinib
  • Flucloxacillin
  • Fosphenytoin-Phenytoin
  • Imatinib
  • Immune Checkpoint Inhibitors
  • Isoniazid
  • LamoTRIgine
  • Local Anesthetics
  • Lorlatinib
  • MetyraPONE
  • Mipomersen
  • Mitapivat
  • Nitric Oxide
  • PHENobarbital
  • Phenylephrine
  • Prilocaine
  • Primidone
  • Probenecid
  • RifAMPin
  • Sodium Nitrite
  • SORAfenib
  • Vaccines
  • Vitamin K Antagonists


Following recommended dosages is essential to prevent excessive acetaminophen intake, which can harm the liver. 

Inform your doctor of any history of liver issues, hypovolemia, or G6PD deficiency.

If you have allergies to ingredients like aspartame, polysorbate 80, or propylene glycol, use caution.

Side Effects

Common adverse reactions to Tylenol include

  • Acute generalized exanthematous pustulosis
  • Acute hepatic failure
  • Anaphylaxis
  • Erythema of skin
  • Hearing loss
  • Hepatotoxicity
  • Hypersensitivity reaction
  • Increased serum alanine aminotransferase
  • Skin blister
  • Skin rash
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis


  1. Tylenol [package insert]. Johnson & Johnson; 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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