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Tykerb (Lapatinib Ditosylate)

Prescription medicineOnly Available By Prescription
Sezzle

Top brand choice

Strength Pack Size Qty
Strength
250mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Tykerb is a prescription drug that belongs to the class Tyrosine Kinase Inhibitor (TKI). It is used for the treatment of different types of cancer. This drug can be used to treat metastatic breast cancer in combination with other medications.

This drug should only be prescribed by healthcare providers specializing in the treatment of cancer. There are many risks when taking this medication.

Tykerb works by inhibiting endothelial growth factor receptor (EGFR), which is a protein involved in the growth of new cells. By blocking this protein, Tykerb prevents the replication of cancer cells.

Fact Table

Formula

C29H26ClFN4O4S

License

US FDA, EU EMA

Bioavailability

Variable

Legal status

Rx-only

Chemical Name

Lapatinib

Elimination half-life

24 hours

Dosage (Strength)

250mg

Pregnancy

Consult Doctor

Brands

Tykerb, Tyverb

Protein binding

More than 99%

PubChem CID

208908

MedlinePlus

a607055

ChEBI

49603

ATC code

L01EH01

DrugBank

DB01259

KEGG

D08108

Routes of administration

By mouth (tablets)

Directions

Take Tykerb exactly as prescribed by your healthcare provider.

Ingredients

The active ingredient in Tykerb is lapatinib ditosylate.

Interactions

Tell your doctor and pharmacist if you are taking any of the following:

  • Afatinib
  • Alpelisib
  • Berotralstat
  • Bilastine
  • Cladribine
  • Colchicine
  • CYP3A4 Inducers
  • Dexamethasone
  • Digoxin
  • Doxorubicin
  • Fexinidazole
  • Fusidic Acid
  • Grapefruit Juice
  • Lefamulin
  • Lemborexant
  • Lomitapide
  • Lonafarnib
  • Pazopanib
  • Pimozide
  • Relugolix
  • Relugolix, Estradiol, and Norethindrone
  • Rimegepant
  • Sirolimus
  • Sirolimus
  • St John's Wort
  • Topotecan
  • Ubrogepant
  • Venetoclax
  • Vincristine

Cautions

Tell your doctor if you have heart problems before starting this drug.

Tell your doctor if you have a history of liver problems.

Diarrhea is a common and severe side effect of this drug.

Use caution if you have a history of lung disease.

Side Effects

The most common side effects may include:

  • Alopecia
  • Anaphylaxis
  • Anorexia
  • Asthenia
  • Back pain
  • Decreased hemoglobin
  • Decreased left ventricular ejection fraction
  • Decreased neutrophils
  • Decreased platelet count
  • Diarrhea
  • Dyspepsia 
  • Dyspnea
  • Epistaxis
  • Fatigue
  • Hepatotoxicity
  • Hypersensitivity reaction
  • Increased serum alanine aminotransferase
  • Increased serum aspartate aminotransferase
  • Increased serum bilirubin
  • Insomnia
  • Interstitial pulmonary disease
  • Limb pain
  • Nail disease
  • Nausea
  • Palmar-plantar erythrodysesthesia 
  • Paronychia
  • Pneumonitis
  • Prolonged QT interval
  • Pruritus
  • Skin fissure
  • Skin rash
  • Stevens-Johnson syndrome
  • Stomatitis
  • Toxic epidermal necrolysis
  • Ventricular arrhythmia
  • Vomiting
  • Xeroderma 

Buy Tykerb from Canada Drugs Direct

References

  1. Tykerb [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2007.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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