Tukysa (Tucatinib)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Tukysa is a prescription medication that is used in combination with:

  • Trastuzumab and capecitabine to treat metastatic breast cancer, including patients who have brain cancer; it is used in adults who have received one or more prior treatment regimens
  • Trastuzumab to treat metastatic colorectal cancer in adults after unresponsiveness to chemotherapy

Tukysa is available in 50 mg and 150 mg oral tablets.


Tukysa should be taken as your doctor has directed. If you have any questions or concerns, talk to your doctor or pharmacist.

It is recommended to take 300 mg orally twice daily, with or without food.

A lower dose may be needed in patients with liver impairment.


The active ingredient in Tukysa is tucatinib.

The core of each tablet contains the following: copovidone, crospovidone, sodium chloride, potassium chloride, sodium bicarbonate, colloidal silicon dioxide, magnesium stearate, and microcrystalline cellulose. The coating of each tablet contains the following: polyvinyl alcohol, titanium dioxide, macrogol/polyethylene glycol, talc, and yellow iron oxide non-irradiated.


According to Tukysa’s most recent Prescribing Information, there are no contraindications.


  • Before taking Tukysa, tell your doctor:
    • About any and all prescription and over-the-counter medications you take
    • About any allergies you have
    • About your past medical history and current health conditions
    • If you are currently pregnant or breastfeeding
  • Severe diarrhea that can result in dehydration, acute kidney injury, and death can be caused by Tukysa.
  • Liver damage may occur with Tukysa.
  • An unborn baby can be harmed by Tukysa. Use birth control methods that are effective while taking Tukysa.

Side Effects

Common Tukysa side effects are as follows: diarrhea, hand-foot syndrome, nausea, liver damage, vomiting, inflamed mouth, decreased appetite, anemia, rash, fatigue, stomach pain, infusion-related reactions, and fever. However, these are not the only side effects that can occur. If you develop side effects that are concerning or won’t go away, speak to your doctor right away.


Tukysa. Bothell, WA: Seagen Inc.; 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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