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Triluron (Sodium Hyaluronate)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Triluron (sodium hyaluronate) is an injection used to treat knee pain due to osteoarthritis in patients who failed to respond well to conservative treatment or to simple pain relievers.

Fact Table







Legal status


Chemical Name

Sodium Hyaluronate

Elimination half-life

3 to 5 min

Dosage (Strength)

2ml Syringe





Protein binding


PubChem CID






ATC code






Routes of administration



Triluron comes in either 2 mL glass vials or 2 mL pre-filled syringes to be injected at the intra-articular space of the knee. Once the syringe packaging or the vial's seal has been opened, Triluron should be used immediately. Each vial or syringe is for one use only. Discard immediately after use and discard any remaining quantities. 

Talk to your doctor or pharmacist about any questions you may have. 


There is 20 mg of sodium hyaluronate in each 2 mL glass vial or 2 mL pre-filled syringe.


Avoid using Triluron if you have any allergy to hyaluronate or any other ingredient in Triluron.

Avoid using Triluron if you have had or currently have a skin condition or infection at or near the injection area.


  • Before you start using Triluron, you and your doctor should discuss:
    • If you have any allergies
    • If you take any medications, including prescription and nonprescription medications.
    • Any medical conditions you have
    • If you are pregnant or plan to become pregnant
    • If you are currently breastfeeding or plan to breastfeed your baby
  • Triluron should be administered using a strict and sterile technique to prevent infection at the injection site.
  • Avoid using Triluron with disinfectants that contain quaternary ammonium salts for the skin. This can lead to the precipitation of hyaluronate.
  • After injecting Triluron, joint pain and/or swelling may occur. 
  • After injecting Triluron, inflammation in the knee may occur if you have rheumatoid arthritis or gouty arthritis. 
  • Avoid strenuous activities after at least 48 hours of injecting Triluron.
  • Avoid storing Triluron in light. Store in temperatures below 77°F (25° C). It should not be stored in a freezer.

Side Effects

Triluron injections can cause some side effects, including stomach trouble, pain or discomfort at the injection site, swelling of the knee, headache, itchy skin, and rash.

Immediately talk to your doctor if you experience any worsening or persistent side effects.


  1. Triluron Prescribing Information. Florham Park, NJ: Fidia Pharma USA Inc.; 2019.
  2. Triluron Patient Information. Florham Park, NJ: Fidia Pharma USA Inc.; 2019.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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