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Tremfya (Guselkumab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Tremfya (Guselkumab) is a monoclonal antibody medication used for the treatment of moderate to severe plaque psoriasis. As a biologic medication, it is derived from parts of living cells. Guselkumab works by targeting interleukin-23, a protein that plays a role in the development of plaque psoriasis. By blocking this protein, Tremfya helps to reduce inflammation and slow the overproduction of skin cells associated with the condition.

Fact Table




US DailyMed



Legal status


Chemical Name


Elimination half-life

17 days

Dosage (Strength)

prefilled syringe single-dose 100mg/mL, one-Press patient-controlled injector single-dose 100mg/mL


Consult Doctor



Protein binding


PubChem CID

Not Assigned




Not Assigned

ATC code






Routes of administration



Tremfya comes as a single-dose prefilled syringe containing one 100 mg dose. It is important to use the syringe only once and dispose of it after administering the dose, even if there is medicine left in it.

Before using Tremfya, carefully read and follow the instructions provided by your healthcare provider. The medication must be injected under the skin, usually in the front of the thigh, upper arm, or abdomen. Avoid injecting into areas of the skin that are affected by psoriasis or have damaged skin.

The typical dosing schedule for Tremfya begins with an initial dose, followed by a second dose four weeks later. After the second dose, subsequent injections are usually administered every eight weeks. Always consult your doctor for your specific Tremfya dosing schedule.


The primary active ingredient in Tremfya is Guselkumab. In addition to Guselkumab, Tremfya may contain other ingredients that help stabilize the medication and facilitate its effective administration.


Patients with a history of allergy or hypersensitivity reactions to Guselkumab or any of its components should not take Tremfya.


  • Before starting Tremfya, it’s important to have a detailed discussion with your healthcare provider about:
    • Your current health and any ongoing medical conditions.
    • All medications you’re taking.
  • Any past severe allergic reactions, since Tremfya can cause serious allergies like anaphylaxis. Previous reactions to medications might suggest you're more likely to have a similar response to Tremfya.
  • Tremfya may increase infection risks. If you notice symptoms of a new or worsening infection, contact your healthcare provider right away.
  • Don’t use Tremfya if you have a serious active infection. If an infection develops during treatment, your doctor may stop Tremfya until you recover.
  • Get checked for tuberculosis before starting Tremfya, particularly if you have a history of TB, have been in close contact with someone with TB, or have traveled to areas where TB is common. Tests for TB may include a skin or blood test.
  • Discuss the risks and benefits of using Tremfya if you are pregnant or breastfeeding.
  • Tremfya is used for long-term control of chronic conditions like plaque psoriasis and psoriatic arthritis and is not for sudden flare-ups of these conditions.

Side Effects

Tremfya, like many medications, can lead to a range of side effects from mild to severe. Commonly reported Tremfya side effects include headaches, upset stomach, discomfort in joints, and infections of the respiratory system. You might also notice redness or swelling at the site where Tremfya was injected.

In rare cases, serious side effects can occur. These include severe allergic reactions or infections. If you experience symptoms such as tightness in the chest, swelling of your face or mouth, difficulty breathing, fever, or intense muscle pain, get medical help right away. Please note that this is not an exhaustive list of potential side effects.


  1. Tremfya (Guselkumab) Product Monograph. Horsham, PA: Janssen Biotech, Inc.; 2020.
  2. Tremfya (Guselkumab) Drug Label Information. Horsham, PA: Janssen Biotech, Inc.; 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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