Toujeo (Insulin Glargine)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

TOUJEO (insulin glargine) is a long-acting insulin prescribed to improve glycemic control in people with diabetes mellitus. TOUJEO is indicated for use in patients with type 1 and type 2 diabetes mellitus.


TOUJEO insulin is supplied in a higher concentration than many other types of long-acting insulin. The strength is 300 units per milliliter. For people who need large amounts of insulin, TOUJEO may be more convenient because the volume of medication injected is smaller.

Fact Table

Formula

C267H404N72O78S6

License

US FDA, EMA

Bioavailability

~60–80%

Legal status

Prescription only (Rx-only)

Chemical Name

Insulin Glargine

Elimination half-life

~19 hours (duration of action up to 36 hours)

Dosage (Strength)

300 units/mL (U-300); available in 1.5 mL and 3 mL SoloStar prefilled pens

Pregnancy

Consult a doctor (Category C)

Brands

Toujeo

Protein binding

Low

PubChem CID

16129678

MedlinePlus

a614033

ChEBI

86338

ATC code

A10AE04

DrugBank

DB00047

KEGG

D04557

Routes of administration

Subcutaneous injection

Directions

The prescribing doctor will determine the dosage of TOUJEO. 

Inject TOUJEO under the skin once daily at the same time each day. Do not change the time of injection because TOUJEO lasts approximately 24 hours in most people.

TOUJEO cannot be mixed with other insulin products in the same syringe.

TOUJEO only comes as a pen, called TOUJEO SOLOSTAR, and is not available as a vial.

TOUJEO should be stored in the refrigerator before opening. Once a pen is used for the first time, it should be removed and kept at room temperature for up to 28 days.

Ingredients

The active ingredient in TOUJEO (insulin glargine) is insulin glargine. TOUJEO SOLOSTAR pens hold 450 units or 1.5 milliliters.

Interactions

If you are starting TOUJEO or other insulin medications, tell your doctor if you are also taking any of the following:

  • Alcohol
  • Atypical Antipsychotics
  • Beta-blockers
  • Clonidine
  • Corticosteroids
  • Disopyramide
  • Diuretics
  • Estrogens/Progesterones
  • Fibrates
  • Fluoxetine
  • Isoniazid
  • Lithium
  • Monoamine Oxidase Inhibitors (MAOIs)
  • Niacin
  • Oral antidiabetic agents
  • Pentoxifylline
  • Phenothiazine derivatives
  • Pramlintide
  • Propoxyphene
  • Protease inhibitors
  • Salicylates
  • Somatostatin Analogues
  • Somatropin
  • Sulfonamide Antibiotics
  • Sympathomimetic agents
  • Thyroid replacement medication

Cautions

Watch for signs of low blood sugar (hypoglycemia) while taking TOUJEO or any type of insulin. The symptoms can include:

  • Anxiety
  • Confusion
  • Dizziness
  • Fatigue
  • Hunger
  • Irritability
  • Pale skin
  • Sweating
  • Tremor

Insulin pens should never be shared between patients.

Read the label carefully before injecting TOUJEO to lower the risk of medication errors.

Monitor blood sugar closely when making any change to the anti-diabetic medications, diet, or physical activity.

Side Effects

Common adverse reactions that happen when taking TOUJEO include:

  • Allergic reactions
  • Edema
  • Hypoglycemia
  • Injection site reactions
  • Lipodystrophy
  • Pruritis
  • Rash
  • Weight gain

References

  1. TOUJEO [package insert] Bridgewater, NJ: Sanofi-Aventis; 2015.

Frequently Asked Questions about Toujeo (Insulin Glargine U-300)


Is Toujeo used for both type 1 and type 2 diabetes?

Yes. Toujeo is used in:

Type 1 diabetes: with a rapid-acting insulin
Type 2 diabetes: alone or with other medications


What is the benefit of using a concentrated insulin like Toujeo?

Toujeo delivers the same number of units in a smaller volume, which can:

Improve comfort
Reduce injection site reactions
Benefit people requiring larger doses


How do I switch from Lantus to Toujeo?

Doses are not unit-to-unit equivalent. Your doctor will adjust your Toujeo dose (typically starting at the same unit amount, then titrated). Blood sugar should be closely monitored during the switch.


Can I take Toujeo at night?

Yes. Toujeo can be taken morning or evening, but it should be taken at the same time every day.


Does Toujeo cause weight gain?

Like all insulins, Toujeo may cause mild weight gain due to improved glucose metabolism. This can be managed with healthy diet and exercise.


What happens if I miss a dose of Toujeo?

Take the missed dose as soon as you remember, as long as it’s within 12 hours. If more time has passed, skip the dose and resume the next day. Don’t double-dose.


Is Toujeo safe during pregnancy?

Toujeo may be used in pregnancy, but insulin needs change during each trimester. Always work closely with your doctor if you're pregnant or planning pregnancy.


How does Toujeo compare to Tresiba?

Both are long-acting, but:

Toujeo: Lasts ~36 hours, U-300
Tresiba: Lasts >42 hours, more flexible timing

Your doctor will decide based on your control needs, preferences, and insurance coverage.


Can Toujeo be used in insulin pumps?

No. Toujeo is not approved for use in insulin pumps. It is only for subcutaneous injection via prefilled pen.


What should Toujeo look like before injection?

Toujeo should be clear and colorless. Do not use if it looks cloudy, discolored, or contains particles.

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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