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Tivorbex (Indomethacin)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe Tivorbex to treat mild to moderate pain in adults. Tivorbex is a non-steroidal anti-inflammatory drug (NSAID) and can be used for several different types of acute (short-term) pain.

Fact Table






~100% (oral), 80–90% (rectal)

Legal status


Chemical Name


Elimination half-life

2.6-11.2 hours (adults), 12-28 hours (infants)

Dosage (Strength)



Consult Doctor


Indocid, Indocin, Tivorbex

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


The starting dosage is 20 mg by mouth three times daily. Your doctor may increase the dosage to 40 mg two to three times daily.

Take Tivorbex with food.


The active ingredient in Tivorbex is indomethacin.


There are many drug-drug interactions with Tivorbex, including:

  • Abrocitinib
  • Acemetacin
  • Aminolevulinic Acid 
  • Apixaban
  • Bemiparin
  • Cyclosporine
  • Dabigatran Etexilate
  • Diflunisal
  • Edoxaban
  • Enoxaparin
  • Heparin
  • Ketorolac
  • Lithium
  • Loop Diuretics
  • Macimorelin
  • Methotrexate
  • Mifamurtide
  • Nonsteroidal Anti-Inflammatory Agents
  • Phenylbutazone
  • Pralatrexate
  • Rivaroxaban
  • Salicylates
  • Selective Serotonin Reuptake Inhibitors
  • Sincalide
  • Sodium Phosphates
  • Tenofovir Products
  • Tenoxicam
  • Tiludronate
  • Triamterene
  • Urokinase
  • Vitamin K Antagonists


Use caution if you have a history of cardiovascular disease before starting this drug.

Use caution if you have a history of bleeding conditions.

Tivorbex should be taken at the lowest dose for the shortest amount of time.

Side Effects

Common side effects of this drug can include:

  • Abdominal distress
  • Abdominal pain
  • Acute respiratory distress
  • Alopecia
  • Anaphylaxis
  • Anemia
  • Angioedema
  • Anorexia
  • Anxiety
  • Asthma
  • Auditory disturbance
  • Bloating
  • Blurred vision
  • Breast tenderness
  • Cardiac arrhythmia
  • Cardiac failure
  • Vasculitis
  • Chest pain
  • Confusion
  • Constipation
  • Decreased appetite
  • Depression
  • Diaphoresis
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dyspepsia
  • Dyspnea
  • Ecchymoses
  • Edema
  • Epigastric pain
  • Erythema multiforme
  • Erythema nodosum
  • Exfoliative dermatitis
  • Fatigue
  • Fever
  • Flatulence
  • Fluid retention
  • Flushing
  • Gastroenteritis
  • Gastrointestinal hemorrhage
  • Gastrointestinal perforation
  • Gastrointestinal ulcer
  • Headache
  • Heartburn
  • Hepatic failure
  • Hot flash
  • Hyperglycemia
  • Hyperhidrosis
  • Hyperkalemia
  • Hypertension
  • Hypotension
  • Ileitis
  • Immune thrombocytopenia
  • Insomnia
  • Intestinal obstruction
  • Intestinal stenosis
  • Jaundice
  • Leukopenia
  • Maculopathy
  • Malaise
  • Nausea
  • Nervousness
  • Palpitations
  • Pancreatitis 
  • Paresthesia
  • Peptic ulcer
  • Peripheral neuropathy
  • Postoperative hemorrhage
  • Presyncope
  • Pruritus
  • Psychosis
  • Pulmonary edema
  • Rectal hemorrhage
  • Renal insufficiency
  • Seizure
  • Shock
  • Skin Rash
  • Stevens-Johnson syndrome
  • Swelling
  • Syncope
  • Tachycardia
  • Tinnitus
  • Toxic epidermal necrolysis
  • Urticaria
  • Vaginal hemorrhage
  • Vertigo
  • Vomiting
  • Weight gain


Tivorbex. Philadelphia, PA: Iroko Pharmaceuticals, LLC; 2014.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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