Tivicay (Dolutegravir)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Tivicay is a prescription medication used for the treatment of Human Immunodeficiency Virus type 1 (HIV-1) infection, which is the infection that can lead to Acquired Immunodeficiency Syndrome (AIDS). Tivicay is for use in patients 12 years of age and older and at least 40 kg.

Tivicay is an integrase inhibitor, which means it binds to the protein HIV integrase and blocks the replication of viral DNA. Tivicay is used as part of a combination of drugs for the treatment and suppression of HIV.

Fact Table







Legal status


Chemical Name


Elimination half-life

~14 hours

Dosage (Strength)



Consult Doctor


Tivicay, Tivicay PD

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Take Tivicay exactly as prescribed by your doctor. The usual dosage is 50 mg by mouth one to two times daily. 


The active ingredient in Tivicay is dolutegravir.


Tell your doctor and pharmacist if you are taking any of the following:

  • Aluminum hydroxide
  • Calcium salts
  • Carbamazepine
  • Dalfampridine
  • Dofetilide
  • Efavirenz
  • Etravirine
  • Fosamprenavir
  • Fosphenytoin-Phenytoin
  • Iron preparations
  • Magnesium salts
  • Metformin
  • Multivitamins
  • Nevirapine
  • Oxcarbazepine
  • Phenobarbital
  • Primidone
  • Rifampin
  • Selenium
  • St John's Wort
  • Sucralfate
  • Tipranavir
  • Zinc salts


Do not take this drug if you are taking a medication called dofetilide (Tikosyn).

Take Tivicay 2 hours before or 6 hours after antacids, laxatives, and other drugs that affect digestion.

Tell your doctor if you notice symptoms of body fat redistribution or immune reconstitution syndrome.

Side Effects

Some common Tivicay side effects may include:

  • Increased serum cholesterol
  • Abdominal distress
  • Abdominal pain
  • Abnormal dreams
  • Acute hepatic failure
  • Anxiety
  • Arthralgia
  • Depression
  • Diarrhea
  • Dizziness
  • Fatigue
  • Flatulence
  • Headache
  • Hepatitis
  • Hepatotoxicity
  • Hyperbilirubinemia
  • Hyperglycemia
  • Hypersensitivity reaction
  • Immune reconstitution syndrome
  • Increased creatinine phosphokinase
  • Increased HDL cholesterol
  • Increased LDL cholesterol
  • Increased serum alanine aminotransferase
  • Increased serum aspartate aminotransferase
  • Increased serum creatinine
  • Increased serum lipase
  • Increased serum triglycerides
  • Insomnia 
  • Myalgia
  • Myositis
  • Nausea
  • Neutropenia
  • Pruritus
  • Renal insufficiency
  • Skin rash
  • Suicidal ideation
  • Suicidal tendencies
  • Upper abdominal pain
  • Vomiting
  • Weight gain


Tivicay [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2013.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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