Tilade CFC-Free Inhaler (Nedocromil Sodium)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Tilade Inhaler contains nedocromil sodium, a non-steroidal anti-inflammatory agent indicated for the prophylactic management of asthma. It is used to prevent bronchial inflammation and hyperresponsiveness, particularly in patients with allergic or exercise-induced asthma. Nedocromil stabilizes mast cells and inhibits the release of inflammatory mediators such as histamine and leukotrienes. Tilade is not intended for relief of acute bronchospasm but is effective in reducing the frequency and severity of asthma symptoms when used regularly.

Fact Table

Formula

C19H17NO7•Na2

License

Previously US FDA (withdrawn); available in some other countries

Bioavailability

Low (systemic); acts locally in lungs

Legal status

Prescription (in markets where available)

Chemical Name

Nedocromil Sodium

Elimination half-life

~3.3 hours

Dosage (Strength)

2 mg per actuation; typical dose: 2 puffs 2–4 times daily

Pregnancy

Use if clearly needed; no known fetal risk

Brands

Tilade

Protein binding

~89%

PubChem CID

4413

MedlinePlus

a697011

ChEBI

75230

ATC code

R03BC02

DrugBank

DB01014

KEGG

D00414

Routes of administration

Inhaled (via MDI)

Directions

Tilade Inhaler is typically administered at a dose of two inhalations (4 mg total) twice daily, although dosing may vary based on clinical judgment. The inhaler must be primed before first use and shaken well before each actuation. The medication should be inhaled deeply and held in the lungs for a few seconds to maximize delivery. Regular, scheduled use is essential for effectiveness. Patients should be advised not to use Tilade for immediate relief of asthma attacks and should have a rescue inhaler (e.g., salbutamol) on hand for acute symptoms.

Ingredients

Each actuation delivers:

Nedocromil sodium 2 mg

Inactive ingredients include:

Propellants such as CFC-12, CFC-114, and ethanol in earlier formulations. (Note: Availability and formulation may vary depending on local regulatory status and phase-out of chlorofluorocarbon propellants.)

Contraindications

Tilade is contraindicated in patients with:

Known hypersensitivity to nedocromil sodium or any component of the inhaler

Acute asthma attacks requiring fast-acting bronchodilators

Cautions

Tilade should not be used for rapid symptom relief or during an acute asthma attack. Patients should be instructed on the correct use of the inhaler and advised to adhere to regular dosing, even if asymptomatic. Sudden withdrawal of systemic corticosteroids in patients transitioning to Tilade should be avoided. Monitor for paradoxical bronchospasm, which may require discontinuation. Tilade has limited data on use during pregnancy and should only be used if clearly needed.

Side Effects

Common and potential side effects include:

Throat irritation or coughing

Bad taste or unpleasant aftertaste

Nausea

Headache

Nasal congestion

Rare: paradoxical bronchospasm, rash, or hypersensitivity reactions

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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