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Top Generic choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
10mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Thioridazine is a typical antipsychotic of the phenothiazine class, previously indicated for the treatment of schizophrenia and other psychotic disorders. It exerts its effects primarily through dopamine D2 receptor antagonism in the brain, leading to a reduction in psychotic symptoms such as hallucinations, delusions, and disorganized thinking. Thioridazine also possesses anticholinergic, antiadrenergic, and antihistaminic properties, contributing to both therapeutic and adverse effects. Due to serious cardiac risks, including QT prolongation and fatal arrhythmias, its use is restricted and it has been withdrawn or limited in many countries.
| Fact Table | |
| Formula | C21H26N2S2 |
| License | Withdrawn in U.S. (2005); formerly FDA-approved |
| Bioavailability | ~35–50% |
| Legal status | Discontinued or restricted in most regions |
| Chemical Name | 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-phenothiazine |
| Elimination half-life | ~6–40 hours (highly variable) |
| Dosage (Strength) | 10 mg, 25 mg, 50 mg, 100 mg, 200 mg tablets (discontinued) |
| Pregnancy | Category C – caution advised |
| Brands | Mellaril (brand name, discontinued) |
| Protein binding | ~90–99% |
| PubChem CID | 5452 |
| MedlinePlus | a682119 |
| ChEBI | CHEBI:9587 |
| ATC code | N05AC02 |
| DrugBank | DB00679 |
| KEGG | D08661 |
| Routes of administration | Oral |
Thioridazine should be used only in patients with schizophrenia who have not responded adequately to other antipsychotics.
Each tablet contains:
Inactive ingredients may include:
Thioridazine is contraindicated in:
Boxed Warning: Thioridazine prolongs the QT interval and can cause torsades de pointes, which may be fatal. It should only be used in treatment-resistant schizophrenia when other antipsychotics have failed. Obtain a baseline ECG and monitor potassium and magnesium levels. Use caution in patients with electrolyte imbalances, hepatic dysfunction, or cardiovascular disease. May impair judgment, especially early in treatment. Avoid alcohol and CNS depressants. Not recommended in pediatric patients or during pregnancy unless clearly indicated.
Common and potential side effects include:
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