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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tanzeum (albiglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Albiglutide is a recombinant fusion protein composed of two copies of modified human GLP-1 linked to human albumin, extending its half-life to allow once-weekly subcutaneous administration. It enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying, contributing to improved glycemic control without significant risk of hypoglycemia when used alone.
Note: Tanzeum has been withdrawn from the market by the manufacturer (GlaxoSmithKline) as of 2018 due to commercial reasons, not safety concerns. However, clinical and prescribing information remains relevant for historical and comparative reference.
| Fact Table | |
| Formula | C2530H3852N672O754S16 |
| License | US FDA (withdrawn in 2018) |
| Bioavailability | ~30–35% (subcutaneous) |
| Legal status | Withdrawn (previously Rx-only) |
| Chemical Name | Albiglutide |
| Elimination half-life | 5 days |
| Dosage (Strength) | 30 mg or 50 mg once weekly (subcutaneous injection) |
| Pregnancy | Consult a doctor (Category C) |
| Brands | Tanzeum (US), Eperzan (EU) |
| Protein binding | Not applicable (fusion protein) |
| PubChem CID | 56843331 |
| MedlinePlus | a614040 |
| ChEBI | 143379 |
| ATC code | A10BJ04 |
| DrugBank | DB09045 |
| KEGG | D09725 |
| Routes of administration | Subcutaneous |
The recommended starting dose of Tanzeum was 30 mg administered once weekly via subcutaneous injection in the abdomen, thigh, or upper arm. Based on glycemic response, the dose could be increased to 50 mg once weekly. Tanzeum was supplied as a single-dose kit requiring reconstitution prior to injection. Patients were instructed on proper mixing, handling, and injection technique. It could be used as monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin.
Each Tanzeum injection kit contained a lyophilized powder of albiglutide (30 mg or 50 mg) and a sterile diluent. Inactive ingredients included mannitol, sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous, polysorbate 80, and water for injection.
Tanzeum was contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2). It was also contraindicated in individuals with a prior serious hypersensitivity reaction to albiglutide or any of its components.
Tanzeum carried a boxed warning for the potential risk of thyroid C-cell tumors, as observed in rodent studies, though human relevance remained uncertain. It was not recommended as first-line therapy or for use in patients with type 1 diabetes or diabetic ketoacidosis. Caution was advised in patients with pancreatitis history, severe gastrointestinal disease, or renal impairment. Blood glucose monitoring and patient education on symptoms of pancreatitis (e.g., severe abdominal pain) were recommended.
Use during pregnancy or lactation was not well studied, and Tanzeum was generally avoided in these populations.
Common and serious side effects reported with Tanzeum included:
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