Tabloid (Tioguanine)

Prescription medicineOnly Available By Prescription
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
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  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Tabloid (Thioguanine) is a medication belonging to the purine analog class. It works by disrupting the production of nucleic acids, which hinders the growth of specific cancer cells. Tabloid is often used to help treat certain types of leukemia, a kind of blood cancer. It is mainly given to start and strengthen the initial treatment but is not recommended for long-term use. By integrating into the DNA and RNA of cancer cells, the drug causes cancer cell death and halts the progression of the disease.

Directions

Tabloid is usually taken orally by swallowing the tablets whole with a full glass of water. The dosage is tailored to each individual based on the specific type and stage of cancer being treated, often as part of a combined chemotherapy plan. It is important that Tabloid is used under the supervision of a healthcare provider experienced in cancer treatment.

Patients should strictly adhere to their prescribed dosage schedule. Regular blood tests may be necessary while taking Tabloid to assess its effects on blood cells.

Ingredients

The active ingredient in Tabloid is Thioguanine.

Contraindications

Avoid taking or using Tabloid if any of the following apply:

  • Known hypersensitivity to Thioguanine or any component of the formulation
  • Previous resistance to Thioguanine or Mercaptopurine in the treatment of leukemia

Cautions

  • Before using Tabloid, ensure you provide your healthcare provider with the following information:
    • Existing health conditions
    • Known allergies
    • A list of all the medications you are currently taking
    • Your pregnancy or breastfeeding status
  • Thioguanine should be given under the supervision of a doctor experienced in treating blood cancers, due to the complexity and risks involved.
  • Avoid using Thioguanine for long-term treatments because of the risk of serious liver damage.
  • Before starting Thioguanine, patients often undergo genetic testing to check for enzyme deficiencies that could affect treatment. Regular liver function tests are also necessary.
  • If you experience symptoms such as yellowing of the skin or eyes, fluid retention, or upper belly pain, contact your doctor immediately as these could be signs of liver damage.
  • Frequent blood tests are crucial to monitor for bone marrow suppression, a condition where the bone marrow stops making enough blood cells.
  • Thioguanine can harm an unborn baby, so it's important for women of childbearing age to use effective contraception and avoid pregnancy during treatment.
  • Due to its impact on the immune system, Thioguanine can increase the risk of severe infections. Patients should report any signs of infection to their healthcare provider immediately.
  • Live vaccines should be avoided during Thioguanine treatment because of the increased risk of infection.

Side Effects

Thioguanine commonly reduces all blood cell types, a necessary effect for leukemia management but can lead to complications like infection or bleeding. It often causes high uric acid levels due to rapid tumor cell breakdown, which may be managed with hydration and medications like allopurinol. Other possible Thioguanine side effects include nausea, vomiting, reduced appetite, and mouth sores. Severe but rare issues like intestinal damage can occur.

Long-term use of Thioguanine can lead to serious liver damage, presenting symptoms like jaundice, abdominal swelling, and discomfort. These symptoms are more critical during extended treatments and might improve with stopping the drug. Regular monitoring by a healthcare provider is key to adjust treatment as necessary and prevent severe complications.

References:

  1. Tabloid (Thioguanine) Product Monograph. Mason, OH: Aspen Global, Inc.; 2018.
  2. Tabloid (Tioguanine) Drug Label Information. Mason, OH: Aspen Global, Inc.; 2022.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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