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Synthroid (Levothyroxine)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


SYNTHROID is a replacement for a thyroid hormone that is usually produced by your thyroid gland to regulate the body's energy and metabolism. SYNTHROID contains a chemical called Levothyroxine which is primarily used to treat hypothyroidism (low thyroid hormone). SYNTHROID is also used to prevent and/or treat an enlarged thyroid gland which is referred to as goiter. This medication should not be used to treat weight related problems. It may also be used to treat other conditions as determined by your doctor.


SYNTHROID comes in a tablet form and should be taken orally, exactly as prescribed by your physician. It is recommended to take a tablet once a day in the morning on an empty stomach, an hour before eating. Take the tablet with a full glass of water at the same time each day. SYNTHROID should be taken at least 4 hours apart from drugs that are known to interfere with its absorption.

For children and infants who have difficulty consuming tablets, crush the tablet and mix it with 1-2 teaspoons of water and give it immediately without food or formula.


Before taking SYNTHROID, consult your physician to verify if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

SYNTHROID may not be recommended for certain situations and/or conditions, so share your medical history with your physician. Conditions such as increased thyroid hormones (thyrotoxicosis), decreased adrenal gland function, heart disease (such as coronary artery disease, irregular heartbeat), high blood pressure and diabetes may indicate this medication is not right for you. It is important to consult your physician about any health conditions such as:

  • Diabetes mellitus
  • Low levels of pituitary hormone
  • Heart disease
  • Angina
  • Previous heart attack
  • An unusual or abnormal reaction to SYNTHROID, other thyroid hormones, medications, foods, dyes or preservatives
  • High blood pressure
  • Dieting or on a weight loss program
  • If you are pregnant, breast feeding or currently trying to become pregnant, make sure your doctor is aware of your maternal condition
  • Advise your physician if you are planning to have surgery
  • Tell your doctor about all prescription drugs, nonprescription drugs, and herbal products that you are using

Side Effects

As with any medication, there is the possibility of side effects while using SYNTHROID. If you experience any of the symptoms below and they continue to persist, talk to your physician immediately.

Common side effects of SYNTHROID may include:

  • Tremors
  • Weight loss
  • Nausea and/or vomiting
  • Increased appetite
  • Headache
  • Temporary hair loss
  • Diarrhea
  • Nervousness
  • Irritability
  • Stomach cramps
  • Insomnia
  • Sensitivity to heat
  • Excessive sweating and/or fever
  • Angina or irregular heartbeat
  • Changes in menstrual cycle

The following side effects are rare and should not be taken lightly. If you experience any of these side effects while taking SYNTHROID, consult your physician immediately.

  • Chest pain
  • Nervousness
  • Fast/irregular heartbeat or pulse
  • Excessive sweating or intolerance to heat
  • Skin rash or hives
  • Difficulty breathing, wheezing or shortness of breath
  • Swelling of ankles, feet or legs

Stop using SYNTHROID and get emergency medical help if you have any of these signs of an allergic reaction:.

  • Hives
  • Difficulty breathing
  • Swelling of your face, lips, tongue, or throat

Talk to your doctor about the potential risks associated with this medication.

Frequently Asked Questions about Synthroid (Levothyroxine)

What is Synthroid used for?

Synthroid replaces a hormone your thyroid makes, regulating energy and metabolism. It treats low thyroid hormone levels (hypothyroidism).

What should I avoid when taking Synthroid?

Don't take Synthroid with weight-loss drugs or if you have certain conditions like thyrotoxicosis or symptoms of a heart attack.

What is considered a high dose of Synthroid?

Doses over 200 micrograms daily are generally considered high, but the right dose varies for each person.

How to take Synthroid?

Take Synthroid once daily, before breakfast, on an empty stomach, with only water.

When to take Synthroid?

Take Synthroid 30 to 60 minutes before breakfast, without consuming anything except water.

Does Synthroid cause weight gain?

No, Synthroid doesn't cause weight gain; it helps regulate metabolism and energy levels.

How long after taking Synthroid can I drink coffee?

Wait 30 minutes to 1 hour after taking Synthroid before drinking coffee or consuming other beverages or food.

How long does it take for Synthroid to work?

Symptom improvement may start in a few weeks, but optimal results may take several months.

Is levothyroxine the same as Synthroid?

Yes, levothyroxine is the generic name for Synthroid; both serve the same purpose with the same active ingredient.

What medications should not be taken with Synthroid?

Be cautious with weight-loss drugs, appetite suppressants, and those affecting thyroid function. Always consult your doctor.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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