Supemtek (Quadrivalent Recombinant Influenze Vaccine)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Supemtek is a quadrivalent recombinant influenza vaccine indicated for active immunization to prevent influenza in adults aged 18 years and older. Unlike traditional egg-based influenza vaccines, Supemtek is manufactured using recombinant DNA technology in an insect cell line, allowing for faster production and avoiding mutations associated with egg adaptation. It contains hemagglutinin (HA) antigens from four influenza virus strains (two A subtypes and two B lineages), as recommended annually by the World Health Organization. Supemtek offers an alternative for individuals with egg allergies and has shown favorable immunogenicity and safety in clinical trials.

Fact Table

Formula

Not applicable (recombinant protein vaccine)

License

EMA (EU) – 2020

Bioavailability

High (intramuscular)

Legal status

Prescription only

Chemical Name

Recombinant Influenza Hemagglutinin Antigens (QIV)

Elimination half-life

Not applicable (vaccine)

Dosage (Strength)

0.5 mL single dose containing 45?µg HA per strain (180?µg total)

Pregnancy

Can be used if clearly needed; risk not established

Brands

Supemtek

Protein binding

Not applicable

PubChem CID

Not applicable

MedlinePlus

Not listed

ChEBI

N/A

ATC code

J07BB03

DrugBank

DB15661

KEGG

D11981

Routes of administration

Intramuscular injection

Directions

Supemtek is administered as a single 0.5 mL intramuscular injection, preferably in the deltoid muscle. It should be given annually, ideally before the start of influenza season. Shake the vial gently before use. Do not mix with other vaccines in the same syringe. Supemtek may be co-administered with other vaccines at different injection sites, according to local immunization guidelines. Vaccination should be postponed in individuals with moderate to severe acute illness until recovery.

Ingredients

Each 0.5 mL dose of Supemtek contains:

45 micrograms of recombinant hemagglutinin (rHA) from each of the four influenza virus strains (180 µg total)

Other ingredients include:

Sodium chloride, polysorbate 20, phosphate buffers, and water for injection

Supemtek is preservative-free and does not contain egg proteins, antibiotics, or latex.

Contraindications

Supemtek is contraindicated in patients with:

Known hypersensitivity to any component of the vaccine

A history of severe allergic reaction (e.g., anaphylaxis) to a previous dose of any influenza vaccine

Cautions

Immunization may not protect all recipients, particularly those with immunosuppressive conditions. Use caution in patients with bleeding disorders or those receiving anticoagulant therapy, due to the risk of injection-site hematoma. As with any vaccine, appropriate medical treatment and supervision should be available in the event of an anaphylactic reaction. Individuals should be monitored briefly after vaccination. Supemtek is not approved for use in individuals under 18 years of age.

Side Effects

Common and potential side effects include:

Injection site pain, redness, or swelling

Fatigue

Headache

Myalgia or arthralgia

Nausea

Fever or chills

Rare: hypersensitivity reactions, including anaphylaxis

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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