Sulfatrim (Trimethoprim / Sulfamethoxazole)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Sulfatrim is an antimicrobial medication that is used to treat different types of infections, including:

  • Urinary tract infections
  • Upper and lower respiratory tract infections
  • Gastrointestinal tract infections

Sulfatrim is available in oral tablets that contain 400 mg of sulfamethoxazole USP and 80 mg of trimethoprim USP. Sulfatrim pediatric suspension for oral use is also available to pediatric patients.


Take sulfatrim as your doctor has prescribed. If you have any questions or concerns, speak with your doctor or pharmacist.

Type of infection, age, and weight determine dosage of sulfatrim.

Information concerning how much you should take and how long your treatment should last will be provided to you by your doctor.

A decreased dose may be required for patients with kidney issues.


The active ingredients in sulfatrim are sulfamethoxazole and trimethoprim. Inactive ingredients include colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, and methylcellulose.


If you have an allergy to sulfatrim or any of its ingredients, you should avoid taking it.

If you have ever had immune thrombocytopenia (low platelet counts) due to a drug, you should avoid taking sulfatrim.

Sulfatrim should not be taken with trimethoprim and/or sulfonamides.

If you have megaloblastic anemia caused by a folate deficiency, you should avoid taking sulfatrim.

If you have serious kidney problems, you should avoid taking sulfatrim.

If you are pregnant or breastfeeding, you should avoid taking sulfatrim.

Premature babies and infants younger than 2 months old should not be given sulfatrim.

If you have acute porphyria, avoid taking sulfatrim.


  • Before beginning treatment with sulfatrim, tell your doctor if you:
    • Take any prescription and nonprescription medications
    • Have any allergies
    • Have any health conditions and your medical history
    • Are currently pregnant
    • Are currently breastfeeding
  • Sulfatrim should not be used to treat streptococcal pharyngitis.
  • Sulfatrim can cause severe or potentially life-threatening skin reactions. Immediately get medical attention if you experience any of the following: a flat red rash; blisters; peeling skin; fever; body aches; blisters/sores/ulcers on your mouth, nose, or genitals; and eye inflammation and swelling.
  • Sulfatrim can cause a liver disease called fulminant hepatic necrosis, which causes symptoms such as yellowing of the skin or whites of the eyes; pain in the upper right abdomen, abdominal swelling, nausea, and vomiting. If you experience any of these, immediately seek medical attention.
  • Sulfatrim can cause low white blood cell counts, which can cause fever, chills, sore throat, weakness, fast heart rate, and rapid breathing. If you experience any of these, immediately seek medical attention.
  • Sulfatrim can cause aplastic anemia, which can cause tiredness, shortness of breath, pale skin, easy bruising, fever, chills, sore throat, and a general feeling of discomfort. If you experience any of these, immediately seek medical attention.
  • Immune thrombocytopenia can occur with sulfatrim, causing easy bruising, rash, bleeding of the gums or nose, and blood in the urine or stool. If you experience any of these, immediately seek medical attention.
  • Sulfatrim may cause an allergic reaction in the lungs and airways, causing breathing problems such as coughing, wheezing, and chest tightness. If you experience any of these, immediately seek medical attention.
  • Use caution while driving or operating machinery.
  • Sulfatrim can cause Clostridium difficile-associated diarrhea.

Side Effects

Some of the most common sulfatrim side effects include, but are not limited to, the following: high potassium levels, anorexia, fungal overgrowth, headache, nausea, vomiting, diarrhea, and allergic skin reactions. These are not the only side effects that can occur. If you experience side effects that are concerning or won’t go away, immediately talk to your doctor.


Sulfatrim. Vaughan, Ontario: AA Pharma Inc.; 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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