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Stivarga (Regorafenib)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Stivarga is a prescription medication that is used to help treat metastatic colorectal cancer, gastrointestinal stromal tumor, and liver cancer.

Stivarga is available in 40 mg oral tablets.


Stivarga should be taken as your doctor has instructed. Speak with your doctor or pharmacist if you have any questions or concerns.

Stivarga’s general dose is 160 mg orally once daily for the first 21 days of each 28-day cycle. Stivarga should follow a low-fat meal. Information on how much of the medication you should take will be provided to you by your doctor.


The active ingredient is regorafenib. The inactive ingredients include the following: cellulose microcrystalline,croscarmellose sodium, magnesium stearate, povidone, colloidal silicon dioxide, ferric oxide red, ferric oxide yellow, lecithin (soy), polyethylene glycol 3350, polyvinyl alcohol, talc, and titanium dioxide.


According to the most recent Stivarga Prescribing Information, there are no known contraindications.


The following FDA Boxed Warning is associated with Stivarga:

  • Liver damage that is severe or fatal can occur. Monitoring of liver function should be completed before and during treatment. If liver damage occurs as confirmed by elevated liver enzymes or liver cell necrosis, Stivarga treatment should be stopped or the dose should be decreased based on how severe and persistent the damage is.
  • Before you begin taking Stivarga, tell your doctor if you:
    • Take any prescription or nonprescription medications
    • Have any allergies
    • Have any health conditions and your medical history
    • Are currently pregnant
    • Are currently breastfeeding
  • Warnings and precautions associated with Stivarga include:
    • liver damage
    • worsened infections
    • hemorrhage that can be severe or life-threatening
    • gastrointestinal perforation or fistula
    • skin issues
    • high blood pressure
    • cardiac ischemia or heart attack
    • posterior leukoencephalopathy syndrome
    • impaired wound healing
    • fetal harm; effective contraception should be used during treatment and for 2 months after treatment.

Side Effects

Stivarga side effects include the following: stomach pain, fatigue, diarrhea, decreased appetite, high blood pressure, infection, difficulty speaking, elevated bilirubin levels, fever, inflamed/sore mouth, weight loss, rash, and nausea. These are not the only side effects that can occur. If you develop persistent or concerning side effects, you should speak with your doctor.


Stivarga. Whippany, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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