Stendra (Avanafil)

Also Known as Spedra

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


STENDRA (avanafil) is a medication prescribed to treat erectile dysfunction (ED).

Patients with ED have trouble maintaining or achieving an erection. STENDRA works by enhancing the effects of the chemical signals that are released during sexual arousal. It causes the muscle of blood vessels of the penis to relax, which causes blood to become trapped and produces an erection.


The starting dose of STENDRA pills is 100 mg taken by mouth approximately 30 minutes before sexual activity. STENDRA should not be taken more than once daily. The dose may be adjusted from 50-200 mg per dose based on effectiveness and side effects.

The starting dose of STENDRA is 50 mg if taking drugs that interact including CYP3A4 inhibitors or alpha-blockers (see below).


The active ingredient in STENDRA is avanafil.


STENDRA has potential drug-drug interactions with the following classes of medications:

  • Alcohol
  • Alpha-blockers: doxazosin, prazosin, terazosin
  • Antihypertensive medications
  • Moderate CYP3A4 inhibitors: Erythromycin
  • Nitrates: nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, and food-based sources of nitrates including cured meats
  • Strong CYP3A4 inhibitors: ketoconazole, itraconazole, clarithromycin, nefazodone, ritonavir, saquinavir, nelfinavir, indinavir, atazanavir, telithromycin


Before starting STENDRA, conditions that would make sexual activity inadvisable should be ruled out, like heart problems.

Seek medical attention if you experience priapism, which is an erection lasting longer than four hours. Priapism is a medical emergency.

Stop taking STENDRA and tell your doctor immediately if you experience any change or loss of vision.

Side Effects

The most common side effects of STENDRA include:

  • Back pain
  • Flushing
  • Headache
  • Low blood pressure
  • Nasal congestion
  • Nasopharyngitis


Stendra [package insert]. Mountain View, CA: Vivus; 2012.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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