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Sovaldi (sofosbuvir)

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


SOVALDI (sofosbuvir) is a medication used to treat chronic hepatitis C virus infection. It is approved to treat genotypes 1, 2, 3, or 4 in combination with ribavirin and/or PEG-interferon alfa.

Hepatitis C is a viral infection that causes inflammation of liver cells and sometimes liver damage. Hepatitis C may remain dormant for many years without the infected person's knowledge. It may manifest as an acute hepatitis C infection, which can develop into a chronic infection or resolve on its own.

SOVALDI treats chronic hepatitis C infection by inhibiting the enzyme HCV NS5B RNA-dependent RNA polymerase, a protein enzyme critical to the replication of the hepatitis C virus. Hepatitis C virus utilizes NS5B to replicate viral RNA strands. SOVALDI incorporates into the growing RNA strand during RNA replication, causing termination of the replication process.


Take one 400 mg tablet by mouth once daily with or without food.

The exact regimen and length of therapy are determined by the hepatitis C genotype as well as the physician or treatment team. Take SOVALDI exactly as prescribed by your physician.


The active ingredient of SOVALDI is sofosbuvir.


SOVALDI has the potential for drug interactions with p-glycoprotein inhibitors like rifampin and St. John's Wart. Do not take any new prescription or over-the-medication medications while taking SOVALDI without speaking to your doctor first. Co-administration with p-gp inhibitors may significantly decrease the plasma concentration of SOVALDI and make treatment less effective.

Bradycardia may occur in patients taking both amiodarone and SOVALDI together. Patients taking beta-blockers or those with cardiac abnormalities may be at an increased risk.

Side Effects

Common adverse effects in combination with PEG-interferon alfa and ribavirin:

  • Anemia
  • Chills
  • Decreased appetite
  • Diarrhea
  • Fatigue
  • Headache
  • Influenza-like illness
  • Insomnia
  • Irritability
  • Myalgia
  • Nausea
  • Neutropenia
  • Pruritis
  • Pyrexia
  • Rash

Common adverse effects in combination with ribavirin:

  • Anemia
  • Asthenia
  • Diarrhea
  • Fatigue
  • Headache
  • Insomnia
  • Irritability
  • Myalgia
  • Pruritis
  • Pyrexia

Buy SOVALDI online from Canada Drugs Direct with a valid prescription from your doctor. Compare the SOVALDI price to the price at your local drug store.


  1. Gilead Sciences. Sovaldi [package insert]. U.S. Food and Drug Administration website. Revised 2013. Accessed December 15, 2019.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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