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Sotyktu (Deucravacitinib)

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your dermatologist may have prescribed Sotyktu to treat moderate-to-severe plaque psoriasis. It's recommended for those who might benefit from systemic therapy or phototherapy.

Sotyktu acts as a TYK2 inhibitor, impacting immune responses. It works by targeting TYK2, an important component in the immune system. By stabilizing the protein into a particular shape, Sotyktu helps inhibit immune activity, although the exact workings against psoriasis are still being explored.


The typical dose is 6 mg, taken orally once a day. You can take it with or without food, following your healthcare provider's instructions carefully.

Do not crush, chew, or cut the tablets before administration.


The active ingredient in Sotyktu is deucravacitinib.


Drug-drug interactions can occur between Sotyktu and the following:

  • Adalimumab
  • Azathioprine
  • Basiliximab
  • Belatacept
  • Certolizumab
  • Chickenpox vaccine
  • Ciclosporin
  • Daclizumab
  • Everolimus
  • FluMist (Nasal spray flu vaccine)
  • Golimumab
  • Infliximab
  • Leflunomide
  • Measles, mumps, rubella (MMR) vaccine
  • Methotrexate
  • Mycophenolate mofetil
  • Mycophenolic acid
  • Nasal (nose) spray flu vaccine (FluMist)
  • Rituximab
  • Sirolimus
  • Tacrolimus
  • Tofacitinib
  • Ustekinumab
  • Yellow fever vaccine


Tuberculosis (TB) screening before starting is required due to the increased risk of infectious disease while taking Sotyktu's.

Keep your healthcare provider informed about existing medical conditions or allergies.

Follow the prescribed treatment plan and promptly communicate any unexpected reactions.

Do not stop or adjust treatment without talking to your healthcare provider.

Caution is advised for individuals with a history of muscle wasting or rhabdomyolysis.

Periodic monitoring of liver function tests and cholesterol levels is suggested during treatment.

Tell your doctor if you have a history of lymphoma or other types of cancer before starting this drug.

Tell your doctor if you have a history of kidney or liver problems before starting this drug.

Side Effects

Common adverse reactions may include:

  • Acne
  • Blood creatine phosphokinase increased
  • Folliculitis
  • Herpes simplex
  • Mouth ulcers
  • Upper respiratory infections


Sotyku [package insert]. Princeton, NJ: Bristol-Myers Squibb; 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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