Also Known as Minocin MR
Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
100mg
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Solodyn ER is an extended-release formulation of minocycline hydrochloride, a tetracycline-class antibiotic indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 12 years of age and older. It is not indicated for the treatment of infections or for use in cases of nodular or cystic acne. Solodyn ER provides once-daily oral dosing, delivering therapeutic minocycline levels over 24 hours while minimizing peak-related side effects commonly seen with immediate-release formulations.
| Fact Table | |
| Formula | C23H27N3O7 |
| License | US FDA (2006) |
| Bioavailability | ~90–100% |
| Legal status | Prescription only |
| Chemical Name | Minocycline hydrochloride |
| Elimination half-life | ~15–23 hours |
| Dosage (Strength) | 45 mg, 65 mg, 80 mg, 90 mg, 105 mg, 115 mg, 135 mg ER tablets (based on weight) |
| Pregnancy | Category D – risk of fetal harm; avoid use in pregnancy |
| Brands | Solodyn, generic ER minocycline |
| Protein binding | ~76% |
| PubChem CID | 54675779 |
| MedlinePlus | a682101 |
| ChEBI | CHEBI:44302 |
| ATC code | J01AA08 |
| DrugBank | DB01017 |
| KEGG | D00414 |
| Routes of administration | Oral (extended-release tablets) |
Solodyn ER is administered orally once daily, with or without food.
Do not crush or chew tablets. Avoid taking with antacids, calcium, or iron supplements close to dosing time, as these may impair absorption.
Each tablet contains:
Inactive ingredients may include:
Solodyn ER is contraindicated in:
Use with caution in patients with hepatic dysfunction or those on prolonged therapy, as tetracyclines can cause hepatotoxicity and intracranial hypertension. Monitor for signs of pseudotumor cerebri, particularly in adolescent females. Minocycline may cause photosensitivity—patients should avoid excessive sunlight and use sunscreen. Periodic assessment of liver and renal function, CBC, and clinical response is advised during extended treatment. Drug-induced lupus-like syndrome and autoimmune hepatitis have been reported with minocycline use.
Common and potential side effects include:
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