Skyrizi (risankizumab-rzaa)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Skyrizi is a prescription medication that is used for the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. It’s also used as a treatment for active psoriatic arthritis or moderately to severely active Crohn’s disease in adults.

Skyrizi, an interleukin-23 antagonist, works to prevent the release of inflammatory chemicals.

Skyrizi comes in a subcutaneous injection and is available in prefilled pens, syringes, or cartridges in the following strengths:

  • 150 mg/mL single-dose prefilled pen
  • 75 mg/0.83 mL single-dose prefilled syringe
  • 150 mg/mL single-dose prefilled syringe
  • 180 mg/1.2 mL single-dose prefilled cartridge
  • 360 mg/2.4 mL single-dose prefilled cartridge

Fact Table







Legal status


Chemical Name


Elimination half-life

approximately 28 days

Dosage (Strength)

150 mg/mL single-dose prefilled pen 75 mg/0.83 mL single-dose prefilled syringe 150 mg/mL single-dose prefilled syringe 180 mg/1.2 mL single-dose prefilled cartridge 360 mg/2.4 mL single-dose prefilled cartridge


Consult doctor



Protein binding


PubChem CID





Not Assigned

ATC code






Routes of administration

Subcutaneous injection


Follow your doctor’s instructions on injecting Skyrizi. Talk to your doctor or pharmacist about any questions or concerns you may have about the medication.

Each patient’s Skyrizi dose and duration of treatment is based on their condition. Your doctor will teach you how to properly inject Skyrizi as well as tell you how much medication should be injected and how long your treatment will be.


A humanized immunoglobulin G1 monoclonal antibody, risankizumab-rzaa, is contained in Skyrizi. Skyrizi also contains inactive ingredients; a full list can be found in the package insert.


Skyrizi should not be administered to patients with an allergy to risankizumab-rzaa or to any of the medication’s other ingredients.


  • Before you start using Skyrizi, tell your doctor about:
    • All the prescription and nonprescription medications you take.
    • Your allergies.
    • Your past medical history and current health problems.
    • Your pregnancy or breastfeeding status.
  • Serious allergic reactions, including anaphylaxis, can be caused by Skyrizi. Emergency care should be sought immediately if you have trouble breathing, a rapid heart rate, a rash, or swelling of your lips, tongue, or throat.
  • The risk of infection can be increased with Skyrizi use. If you develop signs or symptoms of an infection, contact your doctor right away.
  • Because Skyrizi can activate tuberculosis (TB), the medication should not be administered to patients with TB.
  • Liver damage can occur with Skyrizi treatment.
  • Patients who are being treated with Skyrizi should avoid receiving live vaccines.

Side Effects

Upper respiratory infections, headache, fatigue, injection site reactions, joint pain, stomach pain, anemia, back pain, fever, joint problems, urinary tract infection, and fungal skin infections are some of the side effects associated with Skyrizi medication; however, patients may experience other side effects. Contact your doctor immediately if you have side effects that bother you or won’t go away.


Skyrizi (risankizumab-rzaa). North Chicago, IL: AbbVie Inc.; 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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