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Skyrizi (risankizumab-rzaa)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Skyrizi is a prescription plaque psoriasis medication that is injected for moderate to severe case relief where the raised, scaly skin patches are more pronounced. It is often recommended when the patient is participating in light therapy for psoriasis or systemic therapy for plaque psoriasis. Prescription for treatment of psoriatic arthritis or for Crohn's disease is possible too. With any treatment application the active ingredient in Skyrizi medication - Risankizumab-Rzaa - functions as an antibody drug that binds to the IL23 inflammatory protein in the body and inhibits its activity. 


Skyrizi dosing typically is on a standard schedule where a single injection is given during the first week of your treatment plan, and with a 2nd injection then given after four weeks. After this 1st Skyrizi injection one is then given every 12 weeks (3 months).

Injection sites can be the front of your thighs (at the top part of your leg between the knee and hip) or the lower part of your abdomen is possible too but make sure the injection is at least 2 inches away from navel. Sitting in a chair when administering the injection is best.


The active ingredient in Skyrizi is Risankizumab-Rzaa.


Inform your doctor of any history of liver problems, tuberculosis, or recurring infections before beginning on Skyrizi medication.

Using Skyrizi may not be an option if you have an upcoming vaccination scheduled.

Use this medication when pregnant or breastfeeding only if a doctor approves it.

Store SKYRIZI in the refrigerator between 36°F to 46°F (2°C to 8°C).

Do not freeze or shake this medication.

Be aware of medication's expiry date.


Negative drug interactions are a possibility between Skyrizi and other Rx medications, including other immunosuppressants and with live vaccines especially. Inform your doctor of all medications and supplements you are currently taking before receiving a prescription and going to buy Skyrizi online.

Side Effects

Side effects from using Skyrizi are a possibility, and some users may have upper respiratory infections, headache, fatigue, injection site reactions, fungal skin infections, injection site reactions, low red blood cells (anemia), fever, back pain, or urinary tract infections. If side effects are experienced it may be best to discontinue use and talk to your doctor again about other plaque psoriasis treatment options.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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