Canada Drugs Direct

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Simparica Trio (Sarolaner ,Moxidectin, Pyrantel)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Dog 2.8-5.5 lbs (Gold Box)
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Dog 5.6-11 lbs (Purple Box)
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Dog 11.1-22 lbs (Caramel Box)
Pack Size
Dog 22.1-44 lbs (Teal Box)
Pack Size
Dog 44.1-88 lbs (Green Box)
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Dog 88.1-132 lbs (Brown Box)
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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Dog owners shouldn’t let their pets be attacked by pesky fleas and ticks. Noticing fleas and ticks along with stopping them as soon as noticed is the best way to keep your pet healthy and happy. A good flea and tick medication is needed, and the best ones will also kill worms in dogs. Simparica Trio for dogs makes the grade there, and it really is one of the most effective medications for preventing fleas and ticks. Heartworms are at the top of the list for dangerous parasite for dogs, and Simparica Trio will kill heartworms, roundworms, and hookworms too. Being a flea and tick chewable solution dogs eat once a month makes it the simplest and most effective approach for flea and tick prevention.

You can buy Simparica Trio with a vet’s prescription at most pharmacies, but a lower Simparica Trio cost may be possible when you order pet medication online from Canada Drugs Direct.


Begin by purchasing the correct dosage strength based on how much your dog weighs. Give your dog 1 Simparica trio chewable flea and tick tablet once a month and aim to do that at the same time each month.

You also have the option of mixing this flea and tick chewable into dog food.


The ingredients in Simparica Trio for Dogs are Moxidectin, Sarolaner, and Pyrantel.


For dogs 8 weeks old and weighing 2.8lbs or more

Never exceed dosage specification - only one Simparica Trio flea and tick per month.

Use only the product indicated for your dog’s body weight.

Let your veterinarian know if your dog has a history of seizures before getting a prescription for Simparica Trio. Sarolaner is an Isoxazoline class drugs that may promote adverse neurologic reactions in these cases.

Only use Simparica Trio with breeding, pregnant, or lactating dogs if your veterinarian approves use of the medication after evaluating your dog.


There are no drug interaction risks established between Simparica Trio and other Rx pet medications. It is advisable to always tell your veterinarian about all medications your dog is currently taking before getting your prescription and you then proceeding to buy Simparica Trio.

Side Effects

It is uncommon to experience side effects from Simparica Trio for dogs, but some dogs may experience vomiting or diarrhea. Side effects that continue or worsens should cause you to discontinue use of this flea and tick worm medication and speak with your veterinarian again regarding other flea and tick prevention options.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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