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Sialor (Anetholtrithion Trithione)


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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Anethal Trithione (brand name Sialor) is a prescription medication designed to treat oral health concerns through its sialogogue properties. In other words, it increases the saliva production in patients who experience side effects from other medications that cause xerostomia (dry mouth). 

Dry mouth can be extremely uncomfortable. The condition may or may not be painful. It may become more difficult to eat or swallow.

Dry mouth can arise from various causes, including medications and underlying health issues. Through its salivary stimulation, Anethal Trithione fosters improved speech, swallowing, and digestion, ultimately minimizing the risk of dental decay and supporting comprehensive oral health.

The mechanism of action of Sialor is unclear, but it is thought to increase the number of muscarinic receptors on salivary acinar cells. Sialor also appears to increase substance P and alpha-calcitonin gene-related peptide, which are involved in saliva production.


The usual dosage is 25 mg by mouth three times daily before meals. If soft stools occur, reduce the dosage to 25 mg with the morning and evening meals.

It typically takes several days for the full effects to occur.

Treatment is typically daily but may be interspersed with five drug-free days per month.


The active ingredient in Sialor is Anethol trithione.


  • There are no known drug-drug interactions between Sialor and other medications.


Tell your doctor about any health conditions you have before starting this drug. Examples include cardiovascular disease, kidney disease, liver disease, history of cancer, or other conditions.

Use caution if you are pregnant or breastfeeding. Speak with your doctor before starting this drug.

Do not take Sialor if you are allergic to any of the ingredients in Sialor.

Side Effects

Common side effects of this drug may include:

  • Diarrhea
  • Discoloration of urine
  • Stool softening


Sialor [prescribing information]. Montreal, Quebec: Pharmascience; 2003.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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