Ryzodeg (Insulin)

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


RYZODEG 70/30 (Insulin degludec and insulin aspart) is a drug prescribed to people with diabetes mellitus. RYZODEG can be used by people with type 1 or type 2 diabetes.

RYZODEG treats high blood sugar and regulates glycemic control. It contains a long-acting insulin and mealtime insulin. RYZODEG is best for people that need both types of insulin and also have a stable diet. RYZODEG may reduce the number of daily shots required for blood sugar control.


Inject RYZODEG under the skin once or twice daily as directed by the prescriber. Rotate injection sites to avoid the side effects of localized cutaneous amyloidosis and lipodystrophy.

Take RYZODEG with the largest meal of the day. If the dose is adjusted, it should not be changed more often than every 3 to 4 days. RYZODEG can be taken with a different meal the next day, as long as they are no longer than 8 hours apart, and it is the largest of the day.


RYZODEG injection contains two active ingredients:

  • 70% insulin degludec, a long-acting insulin
  • 30% insulin aspart, a rapid-acting insulin


Patients who use insulin are at a high risk of low blood sugar (hypoglycemia), so it is essential to be aware of the signs and symptoms. Certain medications can mask these symptoms, so tell your doctor if you are taking:

  • Beta-blockers
  • Clonidine
  • Guanethidine
  • Reserpine

Some drugs can affect the blood sugar of people with diabetes. Taking these drugs with insulin may require a dosage adjustment of RYZODEG. Examples include:

  • Alcohol
  • Atypical Antipsychotics
  • Corticosteroids
  • Disopyramide
  • Diuretics
  • Estrogens/Progesterones
  • Fibrates
  • Fluoxetine
  • Isoniazid
  • Lithium
  • Monoamine Oxidase Inhibitors (MAOIs)
  • Niacin
  • Oral antidiabetic agents
  • Pentoxifylline
  • Phenothiazine derivatives
  • Pramlintide
  • Propoxyphene
  • Protease inhibitors
  • Salicylates
  • Somatostatin Analogues
  • Somatropin
  • Sulfonamide Antibiotics
  • Sympathomimetic agents
  • Thyroid replacement medication


Do not mix or dilute RYZODEG with other insulin products.

RYZODEG cannot be used to treat diabetic ketoacidosis.

Monitor blood sugar frequently while taking RYZODEG. The dosage may need to be adjusted when there are significant changes to physical activity, diet, or other lifestyle factors.

Tell your doctor if you have a history of heart disease, kidney disease, or liver disease.

Side Effects

Common adverse reactions to RYZODEG 70/30 may include:

  • Allergic reactions
  • Edema
  • Hypoglycemia
  • Injection site reactions
  • Lipodystrophy
  • Pruritis
  • Rash
  • Weight gain


Ryzodeg 70/30 [package insert]. Plainsboro, NJ: Novo Nordisk; 2019.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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