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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Rybelsus is a GLP-receptor agonist prescription medication. It is used for treatment of Type 2 diabetes and works to manage blood sugar levels. It functions very differently from similar diabetes medications, particularly with its unique 3-way approach to lowering blood sugar. The advantage of Rybelsus is with how it promotes increased insulin production from the pancreas, reduces the amount of sugar released from the liver, and slows the release of food from the stomach after a meal.

GLP-1 stands for glucagon-like Peptide 1, and Rybelsus mimics your body's naturally occurring GLP-1 to lower blood sugar. Rybelsus is not suited as a primary treatment for Type 2 diabetes, and instead should be added as a supplement to other primary diabetic medications when advised to do so by a physician.

Fact Table







Legal status

RX Only

Chemical Name


Elimination half-life

1 week

Dosage (Strength)

3mg (30 or 90 tablets), 7mg (30 or 90 tablets), 14mg (30 or 90 tablets)


Consult a doctor



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth (tablets)


Take Rybelsus on an empty stomach shortly after you wake up. Take this diabetes medication with no more than 4 ounces of water. Wait one half-hour (30 min.) before eating, drinking, or taking other medications. It is okay to miss a dose, but be sure to take your next dose of Rybelsus at the same the next day.


The active ingredient in Rybelsus for Type 2 diabetes is Semaglutide.


Refrain from use of Rybelsus as a blood sugar lowering medication in either situation; if you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Avoid using Rybelsus is you are allergic to Semaglutide or any of the ingredients in this Type 2 diabetes medication.

Keep Rybelsus tablets in the blister pack until you will be taking them / Push tablet out of blister. Do not cut from the packaging / Swallow tablet whole with cutting, crushing, or chewing.

Store at room temperature 68°F–77°F (20°C–25°C).

Store in a dry place without moisture.


There are no established interaction risks between Rybelsus medication for Type 2 diabetes and other Rx drugs but be sure to inform your doctor of all medicines and supplements you are taking before receiving your prescription for Rybelsus.

Side Effects

Side effects related to the use of this blood sugar lowering medication are uncommon. However, some may experience nausea, stomach (abdominal) pain, diarrhea, decreased appetite, vomiting, and constipation.

Should these symptoms or more serious ones occur, then you must discontinue use of the medication immediately and meet with your doctor again to discuss other blood glucose lowering medication options.

Frequently Asked Questions about Rybelsus (semaglutide)

What is Rybelsus ?

Rybelsus, also called semaglutide, is a daily pill for adults with type 2 diabetes. It assists in controlling blood sugar when used with diet and exercise.

What is the difference between Rybelsus and Ozempic?

Rybelsus and Ozempic are medications for type 2 diabetes. They both have semaglutide, a GLP-1 agonist. Rybelsus is a daily pill, while Ozempic is a weekly shot. Both lead to notable weight loss.

Is Rybelsus the same as wegovy?

Rybelsus and Wegovy both have semaglutide. However, they're used for different reasons: Rybelsus treats type 2 diabetes in adults, while Wegovy is for chronic weight management in certain adults and adolescents. Wegovy is given as a weekly shot and leads to more significant weight loss.

Is Rybelsus (Semaglutide) safe?

Animal studies hint at a thyroid cancer risk, but human research is uncertain. Generally, Rybelsus offers favorable benefits for diabetes patients. If you have a history of thyroid cancer or other health issues, consult your doctor for tailored treatment advice.

How much weight can you lose with Rybelsus?

Although not primarily intended for weight loss, Rybelsus has been linked to an average weight reduction of 5 pounds (2.3 kg) with the 7 mg dose and 8.1 pounds (3.7 kg) with the 14 mg dose. It functions by promoting a feeling of fullness after meals and falls under the category of GLP-1 receptor agonists.

What is Rybelsus used for?

Rybelsus (semaglutide) is prescribed for type 2 diabetes. It boosts insulin release, lowers liver sugar production, and delays stomach emptying post-meals. Before beginning, consult your healthcare provider. Note that it's not for type 1 diabetes or those with a history of pancreatitis.

Does Rybelsus work if you drink water?

Yes, Rybelsus is effective when taken with water. To ensure optimal absorption, it's crucial to take it on an empty stomach, 30 minutes before eating, along with a small amount of water.

What are the side effects of Rybelsus?

Common side effects of Rybelsus (semaglutide) may include nausea, vomiting, diarrhea, abdominal pain, constipation, and decreased appetite. Additionally, there's a risk of thyroid C-cell tumors, particularly in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.

Is Rybelsus available in canada?

Yes, Rybelsus (semaglutide tablets) is available in Canada! Health Canada has approved it as a treatment for adults with type 2 diabetes mellitus, in combination with diet and exercise. Rybelsus is the first and only tablet form of a glucagon-like peptide-1 (GLP-1) analogue.

Which is safer Ozempic or Rybelsus?

Ozempic is suggested for individuals with heart disease because it has FDA-approved benefits of reducing the risk of heart attacks and strokes in type 2 diabetes. Rybelsus does not have this specific approval.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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