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Rukobia (Fostemsavir)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Fostemsavir, commercially known as Rukobia, is a prescription medication specifically indicated for the treatment of HIV-1. Fostemsavir is prescribed for patients who are considered "treatment-experienced," having previously undergone other HIV-1 treatments. It is part of the antiretroviral drug class.

Fostemsavir is usually only prescribed by a specialist who specializes in infectious diseases.


The typical dosage for Fostemsavir is one tablet (600 mg) taken orally twice daily. It can be taken with or without food for flexibility in administration.


The active ingredient is fostemsavir.


Drug-drug interactions with this medication may include

  • Alpelisib
  • Asunaprevir
  • Atogepant
  • Berotralstat
  • Brincidofovir
  • Cladribine
  • Elagolix, Estradiol, and Norethindrone
  • Elbasvir and Grazoprevir
  • Eluxadoline
  • Ethinyl Estradiol-Containing Products
  • Haloperidol
  • Methadone
  • Momelotinib
  • PAZOPanib
  • QT-prolonging Agents
  • Revefenacin
  • Statins
  • St John's Wort


Those with a history of hepatitis B or hepatitis C infection should also inform their healthcare providers.

Patients allergic to any Fostemsavir components should avoid the medication.

Individuals with a history of cardiac problems or taking medications prolonging QTc should consult their doctors before initiating Fostemsavir.

Side Effects

The most common adverse reactions to this medication include

  • Abdominal pain
  • Decreased hemoglobin (grades 3/4)
  • Decreased neutrophils (grades 3/4)
  • Dermatologic: Pruritus, skin rash
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dysgeusia
  • Dyspepsia
  • Fatigue
  • Headache
  • Hypercholesterolemia (grade 3)
  • Hyperglycemia (grades 3/4)
  • Immune reconstitution syndrome
  • Increased direct serum bilirubin (grade 3)
  • Increased LDL cholesterol (grades 3/4)
  • Increased serum alanine aminotransferase (grades 3/4)
  • Increased serum aspartate aminotransferase (grades 3/4)
  • Increased serum bilirubin (grades 3/4)
  • Increased serum creatine kinase (grades 3/4)
  • Increased serum creatinine (grades 3/4)
  • Increased serum lipase (grades 3/4)
  • Increased serum triglycerides (grades 3/4)
  • Increased uric acid (grades 3/4)
  • Leukocyte disorder (grades 3/4)
  • Myalgia
  • Nausea
  • Peripheral Neuropathy
  • Peripheral Sensory Neuropathy
  • Prolonged QT interval
  • Sleep Disturbance
  • Vomiting


Rubokia [package insert]. Research Triangle Park, NC: ViiV Healthcare; July 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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