Also Known as Salofalk Enema
Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
|
Strength
2g/60ml
|
|||
|
Strength
4g/60ml
|
Top Generic choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
|
Strength
4g/60ml
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Rowasa (mesalamine) is a rectal suspension enema for treating adults who suffer from mild to moderate distal ulcerative colitis, proctosigmoiditis, or proctitis.
| Fact Table | |
| Formula |
C7H7NO3 |
| License |
US FDA, EU EMA |
| Bioavailability |
20–30% |
| Legal status |
Rx-Only |
| Chemical Name |
Mesalazine |
| Elimination half-life |
5 hours |
| Dosage (Strength) |
2g/60ml, 4g/60ml |
| Pregnancy |
safe |
| Brands |
Rowasa Enema |
| Protein binding |
43% |
| PubChem CID |
4075 |
| MedlinePlus |
a688021 |
| ChEBI |
6775 |
| ATC code |
A07EC02 |
| DrugBank |
DB00244 |
| KEGG |
D00377 |
| Routes of administration |
rectally |
You should follow the instructions on the label of your prescription and read the package insert that comes with your prescription. If you have any questions or concerns, talk to your doctor or pharmacist.
Rowasa Rectal Suspension Enema comes in disposable bottles that are wrapped in foil trays.
Insert one Rowasa enema rectally once daily at night before you go to bed.
To ensure that the suspension is mixed well, shake the bottle. Remove the applicator tip's protective cover while holding the neck of the bottle. To help with balance, it is recommended to lie on the left side with the left leg stretched out and the upper right leg bent forward. You may alternatively use the knee-chest position.
Gently place the tip of the applicator into the rectum. The applicator tip should point toward the navel. Consistently squeeze the bottle to ensure that you get the optimal amount of medication delivered. Dispose of the used bottle.
Remain in the same position for at least 30 minutes. If possible, retain the enema throughout the entire night.
It is important to stay hydrated during treatment.
Each Rowasa Rectal Suspension Enema consists of 4 grams of mesalamine in 60 mL aqueous suspension.
Carbomer 934P, edetate disodium, potassium acetate, potassium metabisulfite, purified water, and xanthan gum are the inactive ingredients. Sodium benzoate is used as a preservative. There is a protective cover over the applicator tip that contains polyethylene and USP white petrolatum for lubrication.
Avoid using Rowasa if you are allergic to salicylates, aminosalicylates, sulfites, or any other ingredient in Rowasa.
Immediately tell your doctor if you begin to experience troublesome or persistent side effects. The most common side effects associated with Rowasa are the following: stomach pain, cramps, headache, gas, nausea, flu, tiredness, fever, rash, cold, sore throat, diarrhea, leg pain, joint pain, dizziness, bloating, back pain, pain upon enema insertion, hemorrhoids, itching, rectal pain, constipation, hair loss, peripheral swelling, urinary tract infection, burning upon urination, lack of energy, and trouble sleeping.
Rowasa (mesalamine) Rectal Suspension Enema 4.0 grams/unit (60 mL). Somerset, NJ: Meda Pharmaceuticals; 2020.
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