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Rinvoq ER (Upadacitinib)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Rinvoq is a medication prescribed to treat rheumatoid arthritis (RA). Rinvoq is reserved for patients who have tried and failed the medication methotrexate. It can be taken with methotrexate or with other RA medications.

RA is an inflammatory joint condition with symptoms including pain, swelling, redness, and tenderness.

Rinvoq modulates the immune system and makes it less active. Reducing the immune system helps to relieve symptoms of RA. 

Fact Table







Legal status


Chemical Name


Elimination half-life

9–14 hours

Dosage (Strength)



Not Recommended


Rinvoq ER

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


The usual Rinvoq dosing is 15 mg by mouth once daily.

Take Rinvoq exactly as prescribed by your doctor.


Upadacitinib is the active ingredient in Rinvoq.


Rinvoq has many potential drug-drug interactions. Tell your doctor and pharmacist about all of the medications you are taking before starting Rinvoq.

Common drug-drug interactions include:

  • Apalutamide
  • Atazanavir
  • Carbamazepine
  • Ceritinib
  • Clarithromycin
  • Darunavir
  • Enzalutamide
  • Fosphenytoin
  • Idelalisib
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Lonafarnib
  • Lopinavir
  • Lumacaftor
  • Lumacaftor-ivacaftor
  • Mifepristone
  • Mitotane
  • Nefazodone
  • Nelfinavir
  • Ombitasvir-paritaprevir-ritonavir
  • Phenobarbital
  • Phenytoin
  • Posaconazole
  • Primidone
  • Rifampin (rifampicin)
  • Saquinavir
  • Telithromycin
  • Tucatinib
  • Voriconazole


Tell your doctor if you have any latent infections, including tuberculosis or other viral, bacterial, or fungal infections. Rinvoq can re-activate latent infections. 

Rinvoq has been associated with the development of certain types of cancers, including lymphomas.

Medications similar to Rinvoq may increase the risk of blood clots, including deep vein thrombosis, pulmonary embolism, and stroke.

Rinvoq should not be used in combination with potent immunosuppressants like azathioprine and cyclosporine.

Side Effects

Rinvoq is associated with the following side effects:

  • Cough
  • Fever
  • Increased liver enzymes
  • Nausea
  • Pyrexia
  • Upper respiratory tract infection


  1. Rinvoq [package insert]. Whippany, NJ: Abbvie; 2019.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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